Plasmid-free production of the plant lignan pinoresinol in growing Escherichia coli cells

Abstract Background The high-value aryl tetralin lignan (+)-pinoresinol is the main precursor of many plant lignans including (-)-podophyllotoxin, which is used for the synthesis of chemotherapeutics. As (-)-podophyllotoxin is traditionally isolated from endangered and therefore limited natural sour...

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Bibliographic Details
Main Authors: U. Joost Luelf, Alexander Wassing, Lisa M. Böhmer, Vlada B. Urlacher
Format: Article
Language:English
Published: BMC 2024-10-01
Series:Microbial Cell Factories
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Online Access:https://doi.org/10.1186/s12934-024-02562-3
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