Trend of the lipid profile in a cohort with severe hypercholesterolemia in Osona county (Barcelona, Spain), between 2009 and 2021
Abstract Background Various studies confirm that the prevalence of dyslipidemia and other cardiovascular factors is high. Objective To evaluate the trend of the lipid profile (LP) in a cohort with severe hypercholesterolemia and its relationship with lipid-lowering treatment during the period 2009–2...
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2025-01-01
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| Online Access: | https://doi.org/10.1186/s12889-025-21294-6 |
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| author | Jordi Prat-Quinzaños Joan Deniel-Rosanas Pere Roura-Poch Maria-Àngels Casas-Capdevila Victor Farré-Guerrero |
| author_facet | Jordi Prat-Quinzaños Joan Deniel-Rosanas Pere Roura-Poch Maria-Àngels Casas-Capdevila Victor Farré-Guerrero |
| author_sort | Jordi Prat-Quinzaños |
| collection | DOAJ |
| description | Abstract Background Various studies confirm that the prevalence of dyslipidemia and other cardiovascular factors is high. Objective To evaluate the trend of the lipid profile (LP) in a cohort with severe hypercholesterolemia and its relationship with lipid-lowering treatment during the period 2009–2021. Methods Cross-sectional study carried out in the Osona county (Barcelona). Outpatients from the first period (2009–2011) who were aged between 25 and 65 years and had severe hypercholesterolemia were selected (n = 2,608). In a second period (2019–2021), these patients (n = 1,855) were followed up to evaluate the trend of LP and its relationship with lipid-lowering treatment. The Student’s T-test (paired data) was used to identify differences between observations from the two periods. Results Lipid-lowering treatment was prescribed to 61.9% of patients. The group of patients of the cohort improved the data of the mean results of the LP. Approximately 75% of cases were unable to establish their cholesterol and atherogenic fraction values. The prescription of lipid-lowering treatment in the cardiovascular disease group (CVD) was 80.9% vs 61.9% of the total cohort. Conclusion Three out of four cases failed to reduce the levels of LDL-C and non-HDL-C, recommended by the guidelines of scientific societies. Primary Care is the ideal framework to implement improvement strategies to control severe hypercholesterolemia, and it is therefore essential to strengthen it. |
| format | Article |
| id | doaj-art-9aab6a5d9ad446a08c0ff8c397f8df36 |
| institution | Kabale University |
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| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
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| series | BMC Public Health |
| spelling | doaj-art-9aab6a5d9ad446a08c0ff8c397f8df362025-02-02T12:45:59ZengBMCBMC Public Health1471-24582025-01-0125111010.1186/s12889-025-21294-6Trend of the lipid profile in a cohort with severe hypercholesterolemia in Osona county (Barcelona, Spain), between 2009 and 2021Jordi Prat-Quinzaños0Joan Deniel-Rosanas1Pere Roura-Poch2Maria-Àngels Casas-Capdevila3Victor Farré-Guerrero4Laboratory Medicine, Clinical Laboratory, Vic University HospitalFamily and Community Medicine, Manlleu Primary Care CentrePreventive Medicine, Epidemiology Unit, Vic University HospitalClinical Chemistry, Clinical Laboratory, Vic University HospitalLaboratory Medicine, Clinical Laboratory, Vic University HospitalAbstract Background Various studies confirm that the prevalence of dyslipidemia and other cardiovascular factors is high. Objective To evaluate the trend of the lipid profile (LP) in a cohort with severe hypercholesterolemia and its relationship with lipid-lowering treatment during the period 2009–2021. Methods Cross-sectional study carried out in the Osona county (Barcelona). Outpatients from the first period (2009–2011) who were aged between 25 and 65 years and had severe hypercholesterolemia were selected (n = 2,608). In a second period (2019–2021), these patients (n = 1,855) were followed up to evaluate the trend of LP and its relationship with lipid-lowering treatment. The Student’s T-test (paired data) was used to identify differences between observations from the two periods. Results Lipid-lowering treatment was prescribed to 61.9% of patients. The group of patients of the cohort improved the data of the mean results of the LP. Approximately 75% of cases were unable to establish their cholesterol and atherogenic fraction values. The prescription of lipid-lowering treatment in the cardiovascular disease group (CVD) was 80.9% vs 61.9% of the total cohort. Conclusion Three out of four cases failed to reduce the levels of LDL-C and non-HDL-C, recommended by the guidelines of scientific societies. Primary Care is the ideal framework to implement improvement strategies to control severe hypercholesterolemia, and it is therefore essential to strengthen it.https://doi.org/10.1186/s12889-025-21294-6Severe hypercholesterolemiaPrimary careLipid-lowering treatmentCardiovascular disease |
| spellingShingle | Jordi Prat-Quinzaños Joan Deniel-Rosanas Pere Roura-Poch Maria-Àngels Casas-Capdevila Victor Farré-Guerrero Trend of the lipid profile in a cohort with severe hypercholesterolemia in Osona county (Barcelona, Spain), between 2009 and 2021 BMC Public Health Severe hypercholesterolemia Primary care Lipid-lowering treatment Cardiovascular disease |
| title | Trend of the lipid profile in a cohort with severe hypercholesterolemia in Osona county (Barcelona, Spain), between 2009 and 2021 |
| title_full | Trend of the lipid profile in a cohort with severe hypercholesterolemia in Osona county (Barcelona, Spain), between 2009 and 2021 |
| title_fullStr | Trend of the lipid profile in a cohort with severe hypercholesterolemia in Osona county (Barcelona, Spain), between 2009 and 2021 |
| title_full_unstemmed | Trend of the lipid profile in a cohort with severe hypercholesterolemia in Osona county (Barcelona, Spain), between 2009 and 2021 |
| title_short | Trend of the lipid profile in a cohort with severe hypercholesterolemia in Osona county (Barcelona, Spain), between 2009 and 2021 |
| title_sort | trend of the lipid profile in a cohort with severe hypercholesterolemia in osona county barcelona spain between 2009 and 2021 |
| topic | Severe hypercholesterolemia Primary care Lipid-lowering treatment Cardiovascular disease |
| url | https://doi.org/10.1186/s12889-025-21294-6 |
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