Precision Medicine and the Human Proteome in Disease, Diagnostics and Translation: Current Status and Future Prospects
The human proteome—the entire collection of proteins expressed by the human genome—represents a dynamic and intricate landscape of biological function. Proteins are the workhorses of the body, driving processes from cellular communication to immune defense, and their alterations underpin many diseas...
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| Language: | English |
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MDPI AG
2025-05-01
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| Series: | Biomedicines |
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| Online Access: | https://www.mdpi.com/2227-9059/13/5/1130 |
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| author | M. Walid Qoronfleh |
| author_facet | M. Walid Qoronfleh |
| author_sort | M. Walid Qoronfleh |
| collection | DOAJ |
| description | The human proteome—the entire collection of proteins expressed by the human genome—represents a dynamic and intricate landscape of biological function. Proteins are the workhorses of the body, driving processes from cellular communication to immune defense, and their alterations underpin many diseases. Understanding the proteome has become a cornerstone of modern biomedical research, offering insights into disease mechanisms, diagnostic tools, and personalized treatments through precision medicine. This commentary explores the current state of human proteome research; its applications in disease understanding, diagnostics, and therapeutic advancements; and the exciting prospects that lie ahead. |
| format | Article |
| id | doaj-art-9a9fa80e2f82439e8e31af306098645c |
| institution | DOAJ |
| issn | 2227-9059 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Biomedicines |
| spelling | doaj-art-9a9fa80e2f82439e8e31af306098645c2025-08-20T03:14:42ZengMDPI AGBiomedicines2227-90592025-05-01135113010.3390/biomedicines13051130Precision Medicine and the Human Proteome in Disease, Diagnostics and Translation: Current Status and Future ProspectsM. Walid Qoronfleh0Healthcare Research & Policy Division, Q3 Research Institute (QRI), 7227 Rachel Drive, Ypsilanti, MI 48917, USAThe human proteome—the entire collection of proteins expressed by the human genome—represents a dynamic and intricate landscape of biological function. Proteins are the workhorses of the body, driving processes from cellular communication to immune defense, and their alterations underpin many diseases. Understanding the proteome has become a cornerstone of modern biomedical research, offering insights into disease mechanisms, diagnostic tools, and personalized treatments through precision medicine. This commentary explores the current state of human proteome research; its applications in disease understanding, diagnostics, and therapeutic advancements; and the exciting prospects that lie ahead.https://www.mdpi.com/2227-9059/13/5/1130human proteomeproteomicsmulti-omicsproteinsbiomarkersprecision medicine |
| spellingShingle | M. Walid Qoronfleh Precision Medicine and the Human Proteome in Disease, Diagnostics and Translation: Current Status and Future Prospects Biomedicines human proteome proteomics multi-omics proteins biomarkers precision medicine |
| title | Precision Medicine and the Human Proteome in Disease, Diagnostics and Translation: Current Status and Future Prospects |
| title_full | Precision Medicine and the Human Proteome in Disease, Diagnostics and Translation: Current Status and Future Prospects |
| title_fullStr | Precision Medicine and the Human Proteome in Disease, Diagnostics and Translation: Current Status and Future Prospects |
| title_full_unstemmed | Precision Medicine and the Human Proteome in Disease, Diagnostics and Translation: Current Status and Future Prospects |
| title_short | Precision Medicine and the Human Proteome in Disease, Diagnostics and Translation: Current Status and Future Prospects |
| title_sort | precision medicine and the human proteome in disease diagnostics and translation current status and future prospects |
| topic | human proteome proteomics multi-omics proteins biomarkers precision medicine |
| url | https://www.mdpi.com/2227-9059/13/5/1130 |
| work_keys_str_mv | AT mwalidqoronfleh precisionmedicineandthehumanproteomeindiseasediagnosticsandtranslationcurrentstatusandfutureprospects |