Anticancer, antimicrobial and molecular docking analysis of newly synthesized iodoquinazoline derivatives

Anticancer, antimicrobial and molecular docking analysis of newly synthesized iodoquinazoline derivatives

Abstract The 4-anilinoquinazoline sulfonamide derivatives in medicinal chemistry are well-known antitumor backbones via different mechanisms. Herein, we reported the synthesis of five new 2,4-disubstituted-6-iodoquinazoline derivatives coded compounds 3a–e. The respective compounds were examined for...

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Bibliographic Details
Main Authors:	Khaled M. Aboshanab, Amr S. Bishr, Siti Azma Jusoh, Mohammad Y. Alshahrani, Khondaker Miraz Rahman, Ahmed M. Alafeefy
Format:	Article
Language:	English
Published:	SpringerOpen 2025-06-01
Series:	AMB Express
Subjects:	Quinazoline Sulfonamide Carbonic anhydrase Cancer Antimicrobial Molecular docking
Online Access:	https://doi.org/10.1186/s13568-025-01899-1
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