Primary Cardiac Burkitt Lymphoma Presenting with Abdominal Pain

We describe the case of a 44-year-old woman with primary Burkitt lymphoma of the heart who presented with abdominal bloating and epigastric discomfort secondary to tamponade physiology caused by a large pericardial effusion. The pericardial fluid contained a large number of highly atypical lymphocyt...

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Main Authors: Dimitrios Tzachanis, Rajan Dewar, Katarina Luptakova, James D. Chang, Robin M. Joyce
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2014/687598
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author Dimitrios Tzachanis
Rajan Dewar
Katarina Luptakova
James D. Chang
Robin M. Joyce
author_facet Dimitrios Tzachanis
Rajan Dewar
Katarina Luptakova
James D. Chang
Robin M. Joyce
author_sort Dimitrios Tzachanis
collection DOAJ
description We describe the case of a 44-year-old woman with primary Burkitt lymphoma of the heart who presented with abdominal bloating and epigastric discomfort secondary to tamponade physiology caused by a large pericardial effusion. The pericardial fluid contained a large number of highly atypical lymphocytes with moderate basophilic cytoplasm, rare punched-out vacuoles, a vesicular nuclear chromatin, large nucleolus, and marginated chromatin that by FISH were positive for the 8;14 translocation. She had no other sites of disease. She was treated with four alternating cycles of modified CODOX-M and IVAC in combination with rituximab and remains in remission more than 5 years since diagnosis.
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series Case Reports in Hematology
spelling doaj-art-9a6faebdc57f4fec8f135039273f11a32025-02-03T06:42:27ZengWileyCase Reports in Hematology2090-65602090-65792014-01-01201410.1155/2014/687598687598Primary Cardiac Burkitt Lymphoma Presenting with Abdominal PainDimitrios Tzachanis0Rajan Dewar1Katarina Luptakova2James D. Chang3Robin M. Joyce4Cedars-Sinai Medical Center, 8700 Beverly Boulevard, AC1046-A, Los Angeles, CA 90048, USABeth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USABeth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USABeth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USABeth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USAWe describe the case of a 44-year-old woman with primary Burkitt lymphoma of the heart who presented with abdominal bloating and epigastric discomfort secondary to tamponade physiology caused by a large pericardial effusion. The pericardial fluid contained a large number of highly atypical lymphocytes with moderate basophilic cytoplasm, rare punched-out vacuoles, a vesicular nuclear chromatin, large nucleolus, and marginated chromatin that by FISH were positive for the 8;14 translocation. She had no other sites of disease. She was treated with four alternating cycles of modified CODOX-M and IVAC in combination with rituximab and remains in remission more than 5 years since diagnosis.http://dx.doi.org/10.1155/2014/687598
spellingShingle Dimitrios Tzachanis
Rajan Dewar
Katarina Luptakova
James D. Chang
Robin M. Joyce
Primary Cardiac Burkitt Lymphoma Presenting with Abdominal Pain
Case Reports in Hematology
title Primary Cardiac Burkitt Lymphoma Presenting with Abdominal Pain
title_full Primary Cardiac Burkitt Lymphoma Presenting with Abdominal Pain
title_fullStr Primary Cardiac Burkitt Lymphoma Presenting with Abdominal Pain
title_full_unstemmed Primary Cardiac Burkitt Lymphoma Presenting with Abdominal Pain
title_short Primary Cardiac Burkitt Lymphoma Presenting with Abdominal Pain
title_sort primary cardiac burkitt lymphoma presenting with abdominal pain
url http://dx.doi.org/10.1155/2014/687598
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AT jamesdchang primarycardiacburkittlymphomapresentingwithabdominalpain
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