Prevalence of Hypertension and Diabetes and Coexistence of Chronic Kidney Disease and Cardiovascular Risk in the Population of the Republic of Moldova
In 2005, the International Society of Nephrology (ISN) established the Global Outreach Program (GO) aimed at building a capacity for detecting and managing chronic kidney disease and its complications in low- and middle-income countries. Here we report data from the 2006-2007 screening program (1025...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Hypertension |
| Online Access: | http://dx.doi.org/10.1155/2012/951734 |
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| author | Igor Codreanu Vera Sali Sergiu Gaibu Luminita Suveica Sergiu Popa Norberto Perico Bogdan Ene-Iordache Sergio Carminati John Feehally Giuseppe Remuzzi |
| author_facet | Igor Codreanu Vera Sali Sergiu Gaibu Luminita Suveica Sergiu Popa Norberto Perico Bogdan Ene-Iordache Sergio Carminati John Feehally Giuseppe Remuzzi |
| author_sort | Igor Codreanu |
| collection | DOAJ |
| description | In 2005, the International Society of Nephrology (ISN) established the Global Outreach Program (GO) aimed at building a capacity for detecting and managing chronic kidney disease and its complications in low- and middle-income countries. Here we report data from the 2006-2007 screening program (1025 subjects from the general population) in the Republic of Moldova aimed to determine the prevalence of hypertension, diabetes, and their coexistence with microalbuminuria. The likelihood of a serious cardiovascular (CV) event was also estimated. Hypertension and diabetes were very common among screened subjects. The prevalence of microalbuminuria was 16.9% and that of estimated GFR <60 ml/min/1.73 m2 (decreased renal function) was 9.4%. Male gender was associated with an increased prevalence of hypertension and microalbuminuria. Hypertension and diabetes clustered in subjects with microalbuminuria and renal dysfunction. Risk factors such as preobesity/obesity, physical inactivity and smoking were relatively common, even in younger participants. The prevalence of subjects with predicted 10-year CV risk ≥10% was 10.0%. In conclusion, in the Republic of Moldova patients with hypertension and diabetes should be screened for the coexistence of renal abnormalities, with the intention of developing disease-specific health-care interventions with the primary goal to reduce CV morbidity and mortality and prevent renal disease progression to end stage renal disease. |
| format | Article |
| id | doaj-art-9a6aa5b00c7d42d2984df44abd65e708 |
| institution | OA Journals |
| issn | 2090-0384 2090-0392 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Hypertension |
| spelling | doaj-art-9a6aa5b00c7d42d2984df44abd65e7082025-08-20T02:20:15ZengWileyInternational Journal of Hypertension2090-03842090-03922012-01-01201210.1155/2012/951734951734Prevalence of Hypertension and Diabetes and Coexistence of Chronic Kidney Disease and Cardiovascular Risk in the Population of the Republic of MoldovaIgor Codreanu0Vera Sali1Sergiu Gaibu2Luminita Suveica3Sergiu Popa4Norberto Perico5Bogdan Ene-Iordache6Sergio Carminati7John Feehally8Giuseppe Remuzzi9Republican Clinic Hospital, Chisinau, MoldovaRepublican Clinic Hospital, Chisinau, MoldovaRepublican Clinic Hospital, Chisinau, MoldovaMunicipal Council Health Department, Chisinau, MoldovaRepublican Clinic Hospital, Chisinau, MoldovaClinical Research Center for Rare Diseases “Aldo e Cele Daccò” and Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Mario Negri Institute for Pharmacological Research, 24126 Bergamo, ItalyClinical Research Center for Rare Diseases “Aldo e Cele Daccò” and Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Mario Negri Institute for Pharmacological Research, 24126 Bergamo, ItalyClinical Research Center for Rare Diseases “Aldo e Cele Daccò” and Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Mario Negri Institute for Pharmacological Research, 24126 Bergamo, ItalyThe John Walls Renal Unit, Leicester General Hospital, Leicester LE5 4PW, UKClinical Research Center for Rare Diseases “Aldo e Cele Daccò” and Centro Anna Maria Astori, Science and Technology Park Kilometro Rosso, Mario Negri Institute for Pharmacological Research, 24126 Bergamo, ItalyIn 2005, the International Society of Nephrology (ISN) established the Global Outreach Program (GO) aimed at building a capacity for detecting and managing chronic kidney disease and its complications in low- and middle-income countries. Here we report data from the 2006-2007 screening program (1025 subjects from the general population) in the Republic of Moldova aimed to determine the prevalence of hypertension, diabetes, and their coexistence with microalbuminuria. The likelihood of a serious cardiovascular (CV) event was also estimated. Hypertension and diabetes were very common among screened subjects. The prevalence of microalbuminuria was 16.9% and that of estimated GFR <60 ml/min/1.73 m2 (decreased renal function) was 9.4%. Male gender was associated with an increased prevalence of hypertension and microalbuminuria. Hypertension and diabetes clustered in subjects with microalbuminuria and renal dysfunction. Risk factors such as preobesity/obesity, physical inactivity and smoking were relatively common, even in younger participants. The prevalence of subjects with predicted 10-year CV risk ≥10% was 10.0%. In conclusion, in the Republic of Moldova patients with hypertension and diabetes should be screened for the coexistence of renal abnormalities, with the intention of developing disease-specific health-care interventions with the primary goal to reduce CV morbidity and mortality and prevent renal disease progression to end stage renal disease.http://dx.doi.org/10.1155/2012/951734 |
| spellingShingle | Igor Codreanu Vera Sali Sergiu Gaibu Luminita Suveica Sergiu Popa Norberto Perico Bogdan Ene-Iordache Sergio Carminati John Feehally Giuseppe Remuzzi Prevalence of Hypertension and Diabetes and Coexistence of Chronic Kidney Disease and Cardiovascular Risk in the Population of the Republic of Moldova International Journal of Hypertension |
| title | Prevalence of Hypertension and Diabetes and Coexistence of Chronic Kidney Disease and Cardiovascular Risk in the Population of the Republic of Moldova |
| title_full | Prevalence of Hypertension and Diabetes and Coexistence of Chronic Kidney Disease and Cardiovascular Risk in the Population of the Republic of Moldova |
| title_fullStr | Prevalence of Hypertension and Diabetes and Coexistence of Chronic Kidney Disease and Cardiovascular Risk in the Population of the Republic of Moldova |
| title_full_unstemmed | Prevalence of Hypertension and Diabetes and Coexistence of Chronic Kidney Disease and Cardiovascular Risk in the Population of the Republic of Moldova |
| title_short | Prevalence of Hypertension and Diabetes and Coexistence of Chronic Kidney Disease and Cardiovascular Risk in the Population of the Republic of Moldova |
| title_sort | prevalence of hypertension and diabetes and coexistence of chronic kidney disease and cardiovascular risk in the population of the republic of moldova |
| url | http://dx.doi.org/10.1155/2012/951734 |
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