Delayed Hypersensitivity Reaction: An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement

We report the case of a 32-year-old woman who presented with pain recurrence 20 months after she underwent a C5C6 metal-on-metal total replacement. Plan radiographs demonstrated a modification of the shape of the vertebral bodies making the prosthesis more protruding. Then, infection has been ruled...

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Main Authors: Mélodie-Anne Karnoub, Fahed Zairi, Rabih Aboukais, Richard Assaker
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Orthopedics
Online Access:http://dx.doi.org/10.1155/2015/416548
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author Mélodie-Anne Karnoub
Fahed Zairi
Rabih Aboukais
Richard Assaker
author_facet Mélodie-Anne Karnoub
Fahed Zairi
Rabih Aboukais
Richard Assaker
author_sort Mélodie-Anne Karnoub
collection DOAJ
description We report the case of a 32-year-old woman who presented with pain recurrence 20 months after she underwent a C5C6 metal-on-metal total replacement. Plan radiographs demonstrated a modification of the shape of the vertebral bodies making the prosthesis more protruding. Then, infection has been ruled out and patch testing revealed a strongly positive reaction for chromium and cobalt. The prosthesis has been removed and a fusion achieved using a cage filled with bone graft. She has been immediately and fully relieved from her pain. We report the radiological signs that enabled early diagnosis and treatment allowing favorable outcome.
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institution Kabale University
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publishDate 2015-01-01
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series Case Reports in Orthopedics
spelling doaj-art-9a6800757f7e428bbeea61c59cd1f8252025-02-03T05:44:39ZengWileyCase Reports in Orthopedics2090-67492090-67572015-01-01201510.1155/2015/416548416548Delayed Hypersensitivity Reaction: An Increasingly Recognized Complication of Metal-on-Metal Total Disc ReplacementMélodie-Anne Karnoub0Fahed Zairi1Rabih Aboukais2Richard Assaker3Department of Neurosurgery, Lille University Hospital, CHRU de Lille, 59000 Lille, FranceDepartment of Neurosurgery, Lille University Hospital, CHRU de Lille, 59000 Lille, FranceDepartment of Neurosurgery, Lille University Hospital, CHRU de Lille, 59000 Lille, FranceDepartment of Neurosurgery, Lille University Hospital, CHRU de Lille, 59000 Lille, FranceWe report the case of a 32-year-old woman who presented with pain recurrence 20 months after she underwent a C5C6 metal-on-metal total replacement. Plan radiographs demonstrated a modification of the shape of the vertebral bodies making the prosthesis more protruding. Then, infection has been ruled out and patch testing revealed a strongly positive reaction for chromium and cobalt. The prosthesis has been removed and a fusion achieved using a cage filled with bone graft. She has been immediately and fully relieved from her pain. We report the radiological signs that enabled early diagnosis and treatment allowing favorable outcome.http://dx.doi.org/10.1155/2015/416548
spellingShingle Mélodie-Anne Karnoub
Fahed Zairi
Rabih Aboukais
Richard Assaker
Delayed Hypersensitivity Reaction: An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement
Case Reports in Orthopedics
title Delayed Hypersensitivity Reaction: An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement
title_full Delayed Hypersensitivity Reaction: An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement
title_fullStr Delayed Hypersensitivity Reaction: An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement
title_full_unstemmed Delayed Hypersensitivity Reaction: An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement
title_short Delayed Hypersensitivity Reaction: An Increasingly Recognized Complication of Metal-on-Metal Total Disc Replacement
title_sort delayed hypersensitivity reaction an increasingly recognized complication of metal on metal total disc replacement
url http://dx.doi.org/10.1155/2015/416548
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AT fahedzairi delayedhypersensitivityreactionanincreasinglyrecognizedcomplicationofmetalonmetaltotaldiscreplacement
AT rabihaboukais delayedhypersensitivityreactionanincreasinglyrecognizedcomplicationofmetalonmetaltotaldiscreplacement
AT richardassaker delayedhypersensitivityreactionanincreasinglyrecognizedcomplicationofmetalonmetaltotaldiscreplacement