Identification of key genes CCL5, PLG, LOX and C3 in clear cell renal cell carcinoma through integrated bioinformatics analysis

Identification of key genes CCL5, PLG, LOX and C3 in clear cell renal cell carcinoma through integrated bioinformatics analysis

BackgroundClear Cell Renal Cell Carcinoma (ccRCC) is a malignant tumor with high mortality and recurrence rates and the molecular mechanism of ccRCC genesis remains unclear. In this study, we identified several key genes associated with the prognosis of ccRCC by using integrated bioinformatics.Metho...

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Bibliographic Details
Main Authors: Zhenwei Xie, Cheng Feng, Yude Hong, Libo Chen, Mingyong Li, Weiming Deng
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
ccRCC
integrated bioinformatics analysis
hub genes
prognosis
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1587196/full
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