Global research trends on the interaction between gut microbiome and bile acids: a bibliometric and visualized analysis
BackgroundAn increasing number of studies have shown that gut microbiome-bile acids interactions play a crucial role in host health and disease. This bibliometric analysis aims to identify the global scientific output, research hotspots, and frontiers of gut microbiome-bile acids in the past two dec...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-07-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2025.1616995/full |
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| author | Fangli Luo Fangli Luo Fangli Luo Luqiang Sun Renhong Wan Zhen Tian Zhaoxuan He |
| author_facet | Fangli Luo Fangli Luo Fangli Luo Luqiang Sun Renhong Wan Zhen Tian Zhaoxuan He |
| author_sort | Fangli Luo |
| collection | DOAJ |
| description | BackgroundAn increasing number of studies have shown that gut microbiome-bile acids interactions play a crucial role in host health and disease. This bibliometric analysis aims to identify the global scientific output, research hotspots, and frontiers of gut microbiome-bile acids in the past two decades.MethodsWe searched the relevant studies of gut microbiome-bile acids published between 2004 and 2024 in the Web of Science Core Collection database. Microsoft Excel 2019, VOSviewer 1.6.18, Tableau Desktop 2024.2.2, Scimago Graphica 1.0.45, and CiteSpace 6.2.R3 were used to analyze the publications, countries/regions, institutions, journals, authors, references, and keywords.ResultsA total of 4795 original articles and reviews were collected. A visual analysis of the results showed that the number of publications increased rapidly over time. China published the most papers, the United States had the most citations, and the most productive institution was Shanghai Jiaotong University. The most prolific author was Jia Wei, and Jason M. Ridlon was the most frequently co-cited author. Nutrients was the most productive journal. In the keyword co-occurrence network, except for gut microbiome and bile acids, inflammation becomes the keyword with the highest frequency. Keywords and reference analysis show that metabolic diseases (such as obesity and type 2 diabetes mellitus), cancer (such as colorectal cancer), and disease-related mechanisms (such as tgr5 and pathway) are the hot topics and future research trends in this field.ConclusionIn this study, bibliometric analysis was utilized to explore the relationship between gut microbiome and bile acids. The findings can reflect the current hotspots and new directions of gut microbiome-bile acids, and provide an objective description and comprehensive guidance for future related studies. |
| format | Article |
| id | doaj-art-9a3fa325723041bb856432c4ddb88f8a |
| institution | Kabale University |
| issn | 2235-2988 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj-art-9a3fa325723041bb856432c4ddb88f8a2025-08-20T03:34:57ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882025-07-011510.3389/fcimb.2025.16169951616995Global research trends on the interaction between gut microbiome and bile acids: a bibliometric and visualized analysisFangli Luo0Fangli Luo1Fangli Luo2Luqiang Sun3Renhong Wan4Zhen Tian5Zhaoxuan He6Department of Traditional Chinese Medicine, Affiliated Hospital of North Sichuan Medical College, Nanchong, ChinaClinical Medical College of Integrated Traditional Chinese and Western Medicine, North Sichuan Medical College, Nanchong, ChinaCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaDepartment of Traditional Chinese Medicine, Chengdu Wenjiang District Maternal and Child Health Hospital of Traditional Chinese Medicine, Chengdu, ChinaCollege of Acupuncture and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, ChinaBackgroundAn increasing number of studies have shown that gut microbiome-bile acids interactions play a crucial role in host health and disease. This bibliometric analysis aims to identify the global scientific output, research hotspots, and frontiers of gut microbiome-bile acids in the past two decades.MethodsWe searched the relevant studies of gut microbiome-bile acids published between 2004 and 2024 in the Web of Science Core Collection database. Microsoft Excel 2019, VOSviewer 1.6.18, Tableau Desktop 2024.2.2, Scimago Graphica 1.0.45, and CiteSpace 6.2.R3 were used to analyze the publications, countries/regions, institutions, journals, authors, references, and keywords.ResultsA total of 4795 original articles and reviews were collected. A visual analysis of the results showed that the number of publications increased rapidly over time. China published the most papers, the United States had the most citations, and the most productive institution was Shanghai Jiaotong University. The most prolific author was Jia Wei, and Jason M. Ridlon was the most frequently co-cited author. Nutrients was the most productive journal. In the keyword co-occurrence network, except for gut microbiome and bile acids, inflammation becomes the keyword with the highest frequency. Keywords and reference analysis show that metabolic diseases (such as obesity and type 2 diabetes mellitus), cancer (such as colorectal cancer), and disease-related mechanisms (such as tgr5 and pathway) are the hot topics and future research trends in this field.ConclusionIn this study, bibliometric analysis was utilized to explore the relationship between gut microbiome and bile acids. The findings can reflect the current hotspots and new directions of gut microbiome-bile acids, and provide an objective description and comprehensive guidance for future related studies.https://www.frontiersin.org/articles/10.3389/fcimb.2025.1616995/fullbibliometricsgut microbiomebile acidsCitespaceVOSviewervisualization |
| spellingShingle | Fangli Luo Fangli Luo Fangli Luo Luqiang Sun Renhong Wan Zhen Tian Zhaoxuan He Global research trends on the interaction between gut microbiome and bile acids: a bibliometric and visualized analysis Frontiers in Cellular and Infection Microbiology bibliometrics gut microbiome bile acids Citespace VOSviewer visualization |
| title | Global research trends on the interaction between gut microbiome and bile acids: a bibliometric and visualized analysis |
| title_full | Global research trends on the interaction between gut microbiome and bile acids: a bibliometric and visualized analysis |
| title_fullStr | Global research trends on the interaction between gut microbiome and bile acids: a bibliometric and visualized analysis |
| title_full_unstemmed | Global research trends on the interaction between gut microbiome and bile acids: a bibliometric and visualized analysis |
| title_short | Global research trends on the interaction between gut microbiome and bile acids: a bibliometric and visualized analysis |
| title_sort | global research trends on the interaction between gut microbiome and bile acids a bibliometric and visualized analysis |
| topic | bibliometrics gut microbiome bile acids Citespace VOSviewer visualization |
| url | https://www.frontiersin.org/articles/10.3389/fcimb.2025.1616995/full |
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