Severe Metabolic Acidosis: A Case of Triple Hit with Ketogenic Diet, Vinegar, and Metformin in an Obese Patient

Obesity is an epidemic with high burden of disease. It is directly proportional to increased risk of morbidity and mortality. Ketogenic diet and herbal supplements have recently gained popularity amongst patients struggling with weight loss. There are limited data available for most of these supplem...

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Main Authors: Abdul Mughees Rana, Kannan Mansoor, Salman Assad, Mahmoud Abouzid, Iheanyichukwu Ogu, Ghassan Salim Issa Bandak
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Nephrology
Online Access:http://dx.doi.org/10.1155/2020/8861978
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author Abdul Mughees Rana
Kannan Mansoor
Salman Assad
Mahmoud Abouzid
Iheanyichukwu Ogu
Ghassan Salim Issa Bandak
author_facet Abdul Mughees Rana
Kannan Mansoor
Salman Assad
Mahmoud Abouzid
Iheanyichukwu Ogu
Ghassan Salim Issa Bandak
author_sort Abdul Mughees Rana
collection DOAJ
description Obesity is an epidemic with high burden of disease. It is directly proportional to increased risk of morbidity and mortality. Ketogenic diet and herbal supplements have recently gained popularity amongst patients struggling with weight loss. There are limited data available for most of these supplements contrary to the claims laid by the mainstream media. Due to lack of awareness, this patient population is at high risk of adverse effects. We present a case of severe acidosis secondary to ketogenic diet and acetic acid (vinegar) ingestion. The use of dietary acetic acid is usually well tolerated; however, in this case, the large quantities and presence of acute renal injury and metformin use may have worsened the acidosis. Severe ketosis in setting of ketogenic diets is a serious complication, which is infrequently reported in literature. Many of these diets and supplements may seem harmless, but as our case illustrates, when combined with other risk factors, patients can face serious adverse effects and even require hospitalization. It is imperative that such dietary practices are physician supervised to avoid complications. With the recent surge of over-the-counter weight loss supplements and ketogenic diets, physicians also need to engage in dietary discussion with patients when attempting to lose weight.
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series Case Reports in Nephrology
spelling doaj-art-9a3d04a2bf0241f997bfc10ce74501632025-02-03T00:58:44ZengWileyCase Reports in Nephrology2090-66412090-665X2020-01-01202010.1155/2020/88619788861978Severe Metabolic Acidosis: A Case of Triple Hit with Ketogenic Diet, Vinegar, and Metformin in an Obese PatientAbdul Mughees Rana0Kannan Mansoor1Salman Assad2Mahmoud Abouzid3Iheanyichukwu Ogu4Ghassan Salim Issa Bandak5Department of Internal Medicine University Huntington, 1249 15th Street Suite 2000, Huntington, WV 25514, USADepartment of Internal Medicine University Huntington, 1249 15th Street Suite 2000, Huntington, WV 25514, USADepartment of Neurology Marshall University Joan C. Edwards School of Medicine, 1600 Medical Center Drive Office B561, Huntington, WV, USADepartment of Internal Medicine University Huntington, 1249 15th Street Suite 2000, Huntington, WV 25514, USADepartment of Internal Medicine University Huntington, 1249 15th Street Suite 2000, Huntington, WV 25514, USADepartment of Internal Medicine University Huntington, 1249 15th Street Suite 2000, Huntington, WV 25514, USAObesity is an epidemic with high burden of disease. It is directly proportional to increased risk of morbidity and mortality. Ketogenic diet and herbal supplements have recently gained popularity amongst patients struggling with weight loss. There are limited data available for most of these supplements contrary to the claims laid by the mainstream media. Due to lack of awareness, this patient population is at high risk of adverse effects. We present a case of severe acidosis secondary to ketogenic diet and acetic acid (vinegar) ingestion. The use of dietary acetic acid is usually well tolerated; however, in this case, the large quantities and presence of acute renal injury and metformin use may have worsened the acidosis. Severe ketosis in setting of ketogenic diets is a serious complication, which is infrequently reported in literature. Many of these diets and supplements may seem harmless, but as our case illustrates, when combined with other risk factors, patients can face serious adverse effects and even require hospitalization. It is imperative that such dietary practices are physician supervised to avoid complications. With the recent surge of over-the-counter weight loss supplements and ketogenic diets, physicians also need to engage in dietary discussion with patients when attempting to lose weight.http://dx.doi.org/10.1155/2020/8861978
spellingShingle Abdul Mughees Rana
Kannan Mansoor
Salman Assad
Mahmoud Abouzid
Iheanyichukwu Ogu
Ghassan Salim Issa Bandak
Severe Metabolic Acidosis: A Case of Triple Hit with Ketogenic Diet, Vinegar, and Metformin in an Obese Patient
Case Reports in Nephrology
title Severe Metabolic Acidosis: A Case of Triple Hit with Ketogenic Diet, Vinegar, and Metformin in an Obese Patient
title_full Severe Metabolic Acidosis: A Case of Triple Hit with Ketogenic Diet, Vinegar, and Metformin in an Obese Patient
title_fullStr Severe Metabolic Acidosis: A Case of Triple Hit with Ketogenic Diet, Vinegar, and Metformin in an Obese Patient
title_full_unstemmed Severe Metabolic Acidosis: A Case of Triple Hit with Ketogenic Diet, Vinegar, and Metformin in an Obese Patient
title_short Severe Metabolic Acidosis: A Case of Triple Hit with Ketogenic Diet, Vinegar, and Metformin in an Obese Patient
title_sort severe metabolic acidosis a case of triple hit with ketogenic diet vinegar and metformin in an obese patient
url http://dx.doi.org/10.1155/2020/8861978
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