A Case of Anorexia Nervosa with Focal Cortical Dysplasia

Anorexia nervosa (AN) is a fatal condition associated with extreme underweight and undernutrition. It is more common in young females, with a female-to-male ratio of 10 : 1. Focal cortical dysplasia (FCD) is characterized by dysplasia of the cerebral cortex and is a common cause of pharmacoresistant...

Full description

Saved in:
Bibliographic Details
Main Authors: Hiroki Nemoto, Kazuo Imagawa, Takashi Enokizono, Yosuke Masuda, Masayuki Ide, Takuma Deguchi, Monami Hara, Atsushi Morita, Takahiro Kido, Mai Tanaka, Tatsuyuki Ohto, Hidetoshi Takada
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Case Reports in Psychiatry
Online Access:http://dx.doi.org/10.1155/2024/7478666
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832559709400334336
author Hiroki Nemoto
Kazuo Imagawa
Takashi Enokizono
Yosuke Masuda
Masayuki Ide
Takuma Deguchi
Monami Hara
Atsushi Morita
Takahiro Kido
Mai Tanaka
Tatsuyuki Ohto
Hidetoshi Takada
author_facet Hiroki Nemoto
Kazuo Imagawa
Takashi Enokizono
Yosuke Masuda
Masayuki Ide
Takuma Deguchi
Monami Hara
Atsushi Morita
Takahiro Kido
Mai Tanaka
Tatsuyuki Ohto
Hidetoshi Takada
author_sort Hiroki Nemoto
collection DOAJ
description Anorexia nervosa (AN) is a fatal condition associated with extreme underweight and undernutrition. It is more common in young females, with a female-to-male ratio of 10 : 1. Focal cortical dysplasia (FCD) is characterized by dysplasia of the cerebral cortex and is a common cause of pharmacoresistant epilepsy. However, FCD associated with AN has never been reported. We report the first case of AN in a 12-year-old male diagnosed with FCD-type 2 on head magnetic resonance imaging (MRI). He became concerned about lower abdominal distention and began reducing his food intake. He was admitted to our hospital after weight loss of 10 kg in a 1 year. Head MRI showed a localized high-signal area from the cortex to the white matter of the fusiform gyrus near the left hippocampus, with no associated decreased blood flow or electroencephalography (EEG) abnormalities. These findings were characteristic of FCD type II. In males with AN, the search for underlying disease is particularly important. The pathophysiology of the association between AN and FCD is unclear. However, both conditions are reportedly associated with autism spectrum disorder. Further cases are needed to clarify whether FCD is associated with eating disorders.
format Article
id doaj-art-9a1cfd454fde43f385f5eebff2ffa73e
institution Kabale University
issn 2090-6838
language English
publishDate 2024-01-01
publisher Wiley
record_format Article
series Case Reports in Psychiatry
spelling doaj-art-9a1cfd454fde43f385f5eebff2ffa73e2025-02-03T01:29:25ZengWileyCase Reports in Psychiatry2090-68382024-01-01202410.1155/2024/7478666A Case of Anorexia Nervosa with Focal Cortical DysplasiaHiroki Nemoto0Kazuo Imagawa1Takashi Enokizono2Yosuke Masuda3Masayuki Ide4Takuma Deguchi5Monami Hara6Atsushi Morita7Takahiro Kido8Mai Tanaka9Tatsuyuki Ohto10Hidetoshi Takada11Department of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of NeurosurgeryCenter for Medical SciencesDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsAnorexia nervosa (AN) is a fatal condition associated with extreme underweight and undernutrition. It is more common in young females, with a female-to-male ratio of 10 : 1. Focal cortical dysplasia (FCD) is characterized by dysplasia of the cerebral cortex and is a common cause of pharmacoresistant epilepsy. However, FCD associated with AN has never been reported. We report the first case of AN in a 12-year-old male diagnosed with FCD-type 2 on head magnetic resonance imaging (MRI). He became concerned about lower abdominal distention and began reducing his food intake. He was admitted to our hospital after weight loss of 10 kg in a 1 year. Head MRI showed a localized high-signal area from the cortex to the white matter of the fusiform gyrus near the left hippocampus, with no associated decreased blood flow or electroencephalography (EEG) abnormalities. These findings were characteristic of FCD type II. In males with AN, the search for underlying disease is particularly important. The pathophysiology of the association between AN and FCD is unclear. However, both conditions are reportedly associated with autism spectrum disorder. Further cases are needed to clarify whether FCD is associated with eating disorders.http://dx.doi.org/10.1155/2024/7478666
spellingShingle Hiroki Nemoto
Kazuo Imagawa
Takashi Enokizono
Yosuke Masuda
Masayuki Ide
Takuma Deguchi
Monami Hara
Atsushi Morita
Takahiro Kido
Mai Tanaka
Tatsuyuki Ohto
Hidetoshi Takada
A Case of Anorexia Nervosa with Focal Cortical Dysplasia
Case Reports in Psychiatry
title A Case of Anorexia Nervosa with Focal Cortical Dysplasia
title_full A Case of Anorexia Nervosa with Focal Cortical Dysplasia
title_fullStr A Case of Anorexia Nervosa with Focal Cortical Dysplasia
title_full_unstemmed A Case of Anorexia Nervosa with Focal Cortical Dysplasia
title_short A Case of Anorexia Nervosa with Focal Cortical Dysplasia
title_sort case of anorexia nervosa with focal cortical dysplasia
url http://dx.doi.org/10.1155/2024/7478666
work_keys_str_mv AT hirokinemoto acaseofanorexianervosawithfocalcorticaldysplasia
AT kazuoimagawa acaseofanorexianervosawithfocalcorticaldysplasia
AT takashienokizono acaseofanorexianervosawithfocalcorticaldysplasia
AT yosukemasuda acaseofanorexianervosawithfocalcorticaldysplasia
AT masayukiide acaseofanorexianervosawithfocalcorticaldysplasia
AT takumadeguchi acaseofanorexianervosawithfocalcorticaldysplasia
AT monamihara acaseofanorexianervosawithfocalcorticaldysplasia
AT atsushimorita acaseofanorexianervosawithfocalcorticaldysplasia
AT takahirokido acaseofanorexianervosawithfocalcorticaldysplasia
AT maitanaka acaseofanorexianervosawithfocalcorticaldysplasia
AT tatsuyukiohto acaseofanorexianervosawithfocalcorticaldysplasia
AT hidetoshitakada acaseofanorexianervosawithfocalcorticaldysplasia
AT hirokinemoto caseofanorexianervosawithfocalcorticaldysplasia
AT kazuoimagawa caseofanorexianervosawithfocalcorticaldysplasia
AT takashienokizono caseofanorexianervosawithfocalcorticaldysplasia
AT yosukemasuda caseofanorexianervosawithfocalcorticaldysplasia
AT masayukiide caseofanorexianervosawithfocalcorticaldysplasia
AT takumadeguchi caseofanorexianervosawithfocalcorticaldysplasia
AT monamihara caseofanorexianervosawithfocalcorticaldysplasia
AT atsushimorita caseofanorexianervosawithfocalcorticaldysplasia
AT takahirokido caseofanorexianervosawithfocalcorticaldysplasia
AT maitanaka caseofanorexianervosawithfocalcorticaldysplasia
AT tatsuyukiohto caseofanorexianervosawithfocalcorticaldysplasia
AT hidetoshitakada caseofanorexianervosawithfocalcorticaldysplasia