A Case of Anorexia Nervosa with Focal Cortical Dysplasia
Anorexia nervosa (AN) is a fatal condition associated with extreme underweight and undernutrition. It is more common in young females, with a female-to-male ratio of 10 : 1. Focal cortical dysplasia (FCD) is characterized by dysplasia of the cerebral cortex and is a common cause of pharmacoresistant...
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| Format: | Article |
| Language: | English |
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Wiley
2024-01-01
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| Series: | Case Reports in Psychiatry |
| Online Access: | http://dx.doi.org/10.1155/2024/7478666 |
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| author | Hiroki Nemoto Kazuo Imagawa Takashi Enokizono Yosuke Masuda Masayuki Ide Takuma Deguchi Monami Hara Atsushi Morita Takahiro Kido Mai Tanaka Tatsuyuki Ohto Hidetoshi Takada |
| author_facet | Hiroki Nemoto Kazuo Imagawa Takashi Enokizono Yosuke Masuda Masayuki Ide Takuma Deguchi Monami Hara Atsushi Morita Takahiro Kido Mai Tanaka Tatsuyuki Ohto Hidetoshi Takada |
| author_sort | Hiroki Nemoto |
| collection | DOAJ |
| description | Anorexia nervosa (AN) is a fatal condition associated with extreme underweight and undernutrition. It is more common in young females, with a female-to-male ratio of 10 : 1. Focal cortical dysplasia (FCD) is characterized by dysplasia of the cerebral cortex and is a common cause of pharmacoresistant epilepsy. However, FCD associated with AN has never been reported. We report the first case of AN in a 12-year-old male diagnosed with FCD-type 2 on head magnetic resonance imaging (MRI). He became concerned about lower abdominal distention and began reducing his food intake. He was admitted to our hospital after weight loss of 10 kg in a 1 year. Head MRI showed a localized high-signal area from the cortex to the white matter of the fusiform gyrus near the left hippocampus, with no associated decreased blood flow or electroencephalography (EEG) abnormalities. These findings were characteristic of FCD type II. In males with AN, the search for underlying disease is particularly important. The pathophysiology of the association between AN and FCD is unclear. However, both conditions are reportedly associated with autism spectrum disorder. Further cases are needed to clarify whether FCD is associated with eating disorders. |
| format | Article |
| id | doaj-art-9a1cfd454fde43f385f5eebff2ffa73e |
| institution | Kabale University |
| issn | 2090-6838 |
| language | English |
| publishDate | 2024-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Psychiatry |
| spelling | doaj-art-9a1cfd454fde43f385f5eebff2ffa73e2025-02-03T01:29:25ZengWileyCase Reports in Psychiatry2090-68382024-01-01202410.1155/2024/7478666A Case of Anorexia Nervosa with Focal Cortical DysplasiaHiroki Nemoto0Kazuo Imagawa1Takashi Enokizono2Yosuke Masuda3Masayuki Ide4Takuma Deguchi5Monami Hara6Atsushi Morita7Takahiro Kido8Mai Tanaka9Tatsuyuki Ohto10Hidetoshi Takada11Department of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of NeurosurgeryCenter for Medical SciencesDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsDepartment of PediatricsAnorexia nervosa (AN) is a fatal condition associated with extreme underweight and undernutrition. It is more common in young females, with a female-to-male ratio of 10 : 1. Focal cortical dysplasia (FCD) is characterized by dysplasia of the cerebral cortex and is a common cause of pharmacoresistant epilepsy. However, FCD associated with AN has never been reported. We report the first case of AN in a 12-year-old male diagnosed with FCD-type 2 on head magnetic resonance imaging (MRI). He became concerned about lower abdominal distention and began reducing his food intake. He was admitted to our hospital after weight loss of 10 kg in a 1 year. Head MRI showed a localized high-signal area from the cortex to the white matter of the fusiform gyrus near the left hippocampus, with no associated decreased blood flow or electroencephalography (EEG) abnormalities. These findings were characteristic of FCD type II. In males with AN, the search for underlying disease is particularly important. The pathophysiology of the association between AN and FCD is unclear. However, both conditions are reportedly associated with autism spectrum disorder. Further cases are needed to clarify whether FCD is associated with eating disorders.http://dx.doi.org/10.1155/2024/7478666 |
| spellingShingle | Hiroki Nemoto Kazuo Imagawa Takashi Enokizono Yosuke Masuda Masayuki Ide Takuma Deguchi Monami Hara Atsushi Morita Takahiro Kido Mai Tanaka Tatsuyuki Ohto Hidetoshi Takada A Case of Anorexia Nervosa with Focal Cortical Dysplasia Case Reports in Psychiatry |
| title | A Case of Anorexia Nervosa with Focal Cortical Dysplasia |
| title_full | A Case of Anorexia Nervosa with Focal Cortical Dysplasia |
| title_fullStr | A Case of Anorexia Nervosa with Focal Cortical Dysplasia |
| title_full_unstemmed | A Case of Anorexia Nervosa with Focal Cortical Dysplasia |
| title_short | A Case of Anorexia Nervosa with Focal Cortical Dysplasia |
| title_sort | case of anorexia nervosa with focal cortical dysplasia |
| url | http://dx.doi.org/10.1155/2024/7478666 |
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