Regional monitoring of the urinary tract infections causative agents antibiotic resistance in the child population of the Chernivtsi region
In the scope of current medical practice the “viewpoint” regarding the growth of antibiotic resistance of microorganisms is a threat to national security. A reasonable use of antibiotics on the basis of uropathogen regional bacterial sensitivity gives the opportunity to “restrain” the growth of anti...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Zaporizhzhia State Medical and Pharmaceutical University
2017-12-01
|
| Series: | Zaporožskij Medicinskij Žurnal |
| Subjects: | |
| Online Access: | http://zmj.zsmu.edu.ua/article/view/115088/113465 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849695561242902528 |
|---|---|
| author | V. V. Bezruk T. О. Bezruk L. V. Stegnitska S. O. Sokolnyk V. V. Maksymyuk O. I. Godovanets O. S. Godovanets A. I. Kovtun M. I. Sheremet |
| author_facet | V. V. Bezruk T. О. Bezruk L. V. Stegnitska S. O. Sokolnyk V. V. Maksymyuk O. I. Godovanets O. S. Godovanets A. I. Kovtun M. I. Sheremet |
| author_sort | V. V. Bezruk |
| collection | DOAJ |
| description | In the scope of current medical practice the “viewpoint” regarding the growth of antibiotic resistance of microorganisms is a threat to national security. A reasonable use of antibiotics on the basis of uropathogen regional bacterial sensitivity gives the opportunity to “restrain” the growth of antibiotic resistance of microorganisms and increase the effectiveness of the UTI treatment.
The aim of the article is to determine the range and dynamics of the antibiotic resistance of major groups of infectious-inflammatory diseases causative agents of the urinary tract in the child population of the Chernivtsi region.
Materials and methods. The analysis of etiologic spectrum and antibiotic resistance of uropathogens was conducted and observed in the urine samples of 657 patients who were provided with a specialized medical care in the Nephrology department of the “Municipal Children’s Clinical Hospital”, Chernivtsi (2014–2015) with the purpose of the dynamic control of possible changes in the regional antibiotic resistance of pathogens of causative pathogens of the “urinary tract infections” (UTI); identify the age and gender differences of the child population of the Chernivtsi region (2014–2015) compared to the monitoring data for the period of 2009–2013.
Results. When UTI among of the child population of the Chernivtsi region leading etiologic organisms include strains of the family Enterobacteriaceae and uropathogen of the genus Proteus. A “wave-like” curve of the dynamics of antibiotic resistance of Enterobacteriaceae uropathogens with a decreasing tendency to the “drugs of choice” was observed among the child population of the region (2009–2015): penicillin (p < 0.01), cephalosporin II–III generation (p < 0.01) and medicine of the fluoroquinolone series (p < 0.01). A “wave-like” curve of the dynamics of antibiotic resistance of Proteus uropathogens with a decreasing tendency to the “drugs of choice” was observed among the child population of the region (2009–2015): semi-synthetic penicillin (p < 0.1), and medicine of the tetracycline series (p < 0.01).
Conclusions. Regional microbiological monitoring of the uropathogens is an effective “tool” in higher quality treatment of infectious and inflammatory diseases of the urinary tract of the child population. |
| format | Article |
| id | doaj-art-99ff71f407744894a3bf48d45bd146e3 |
| institution | DOAJ |
| issn | 2306-4145 2310-1210 |
| language | English |
| publishDate | 2017-12-01 |
| publisher | Zaporizhzhia State Medical and Pharmaceutical University |
| record_format | Article |
| series | Zaporožskij Medicinskij Žurnal |
| spelling | doaj-art-99ff71f407744894a3bf48d45bd146e32025-08-20T03:19:45ZengZaporizhzhia State Medical and Pharmaceutical UniversityZaporožskij Medicinskij Žurnal2306-41452310-12102017-12-01678078510.14739/2310-1210.2017.6.115088Regional monitoring of the urinary tract infections causative agents antibiotic resistance in the child population of the Chernivtsi regionV. V. BezrukT. О. BezrukL. V. StegnitskaS. O. SokolnykV. V. MaksymyukO. I. GodovanetsO. S. GodovanetsA. I. KovtunM. I. SheremetIn the scope of current medical practice the “viewpoint” regarding the growth of antibiotic resistance of microorganisms is a threat to national security. A reasonable use of antibiotics on the basis of uropathogen regional bacterial sensitivity gives the opportunity to “restrain” the growth of antibiotic resistance of microorganisms and increase the effectiveness of the UTI treatment. The aim of the article is to determine the range and dynamics of the antibiotic resistance of major groups of infectious-inflammatory diseases causative agents of the urinary tract in the child population of the Chernivtsi region. Materials and methods. The analysis of etiologic spectrum and antibiotic resistance of uropathogens was conducted and observed in the urine samples of 657 patients who were provided with a specialized medical care in the Nephrology department of the “Municipal Children’s Clinical Hospital”, Chernivtsi (2014–2015) with the purpose of the dynamic control of possible changes in the regional antibiotic resistance of pathogens of causative pathogens of the “urinary tract infections” (UTI); identify the age and gender differences of the child population of the Chernivtsi region (2014–2015) compared to the monitoring data for the period of 2009–2013. Results. When UTI among of the child population of the Chernivtsi region leading etiologic organisms include strains of the family Enterobacteriaceae and uropathogen of the genus Proteus. A “wave-like” curve of the dynamics of antibiotic resistance of Enterobacteriaceae uropathogens with a decreasing tendency to the “drugs of choice” was observed among the child population of the region (2009–2015): penicillin (p < 0.01), cephalosporin II–III generation (p < 0.01) and medicine of the fluoroquinolone series (p < 0.01). A “wave-like” curve of the dynamics of antibiotic resistance of Proteus uropathogens with a decreasing tendency to the “drugs of choice” was observed among the child population of the region (2009–2015): semi-synthetic penicillin (p < 0.1), and medicine of the tetracycline series (p < 0.01). Conclusions. Regional microbiological monitoring of the uropathogens is an effective “tool” in higher quality treatment of infectious and inflammatory diseases of the urinary tract of the child population.http://zmj.zsmu.edu.ua/article/view/115088/113465urinary tract infectionsantibiotic resistancechildren |
| spellingShingle | V. V. Bezruk T. О. Bezruk L. V. Stegnitska S. O. Sokolnyk V. V. Maksymyuk O. I. Godovanets O. S. Godovanets A. I. Kovtun M. I. Sheremet Regional monitoring of the urinary tract infections causative agents antibiotic resistance in the child population of the Chernivtsi region Zaporožskij Medicinskij Žurnal urinary tract infections antibiotic resistance children |
| title | Regional monitoring of the urinary tract infections causative agents antibiotic resistance in the child population of the Chernivtsi region |
| title_full | Regional monitoring of the urinary tract infections causative agents antibiotic resistance in the child population of the Chernivtsi region |
| title_fullStr | Regional monitoring of the urinary tract infections causative agents antibiotic resistance in the child population of the Chernivtsi region |
| title_full_unstemmed | Regional monitoring of the urinary tract infections causative agents antibiotic resistance in the child population of the Chernivtsi region |
| title_short | Regional monitoring of the urinary tract infections causative agents antibiotic resistance in the child population of the Chernivtsi region |
| title_sort | regional monitoring of the urinary tract infections causative agents antibiotic resistance in the child population of the chernivtsi region |
| topic | urinary tract infections antibiotic resistance children |
| url | http://zmj.zsmu.edu.ua/article/view/115088/113465 |
| work_keys_str_mv | AT vvbezruk regionalmonitoringoftheurinarytractinfectionscausativeagentsantibioticresistanceinthechildpopulationofthechernivtsiregion AT tobezruk regionalmonitoringoftheurinarytractinfectionscausativeagentsantibioticresistanceinthechildpopulationofthechernivtsiregion AT lvstegnitska regionalmonitoringoftheurinarytractinfectionscausativeagentsantibioticresistanceinthechildpopulationofthechernivtsiregion AT sosokolnyk regionalmonitoringoftheurinarytractinfectionscausativeagentsantibioticresistanceinthechildpopulationofthechernivtsiregion AT vvmaksymyuk regionalmonitoringoftheurinarytractinfectionscausativeagentsantibioticresistanceinthechildpopulationofthechernivtsiregion AT oigodovanets regionalmonitoringoftheurinarytractinfectionscausativeagentsantibioticresistanceinthechildpopulationofthechernivtsiregion AT osgodovanets regionalmonitoringoftheurinarytractinfectionscausativeagentsantibioticresistanceinthechildpopulationofthechernivtsiregion AT aikovtun regionalmonitoringoftheurinarytractinfectionscausativeagentsantibioticresistanceinthechildpopulationofthechernivtsiregion AT misheremet regionalmonitoringoftheurinarytractinfectionscausativeagentsantibioticresistanceinthechildpopulationofthechernivtsiregion |