Synthesis, Spectral Studies and Anti-Inflammatory Activity of 2-Acetyl Thiophene

Some new chalcones have been synthesized by the condensation of 2-acetyl thiophene with various aromatic aldehydes in 40% alkali. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-infla...

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Main Authors: B. Ramesh, B. Someswara Rao
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2010/404715
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author B. Ramesh
B. Someswara Rao
author_facet B. Ramesh
B. Someswara Rao
author_sort B. Ramesh
collection DOAJ
description Some new chalcones have been synthesized by the condensation of 2-acetyl thiophene with various aromatic aldehydes in 40% alkali. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.
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institution Kabale University
issn 0973-4945
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language English
publishDate 2010-01-01
publisher Wiley
record_format Article
series E-Journal of Chemistry
spelling doaj-art-99f26245f3c34d0fb7e8619d7e72c73c2025-02-03T06:07:20ZengWileyE-Journal of Chemistry0973-49452090-98102010-01-017243343610.1155/2010/404715Synthesis, Spectral Studies and Anti-Inflammatory Activity of 2-Acetyl ThiopheneB. Ramesh0B. Someswara Rao1Department of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H.Road, Tumkur-572102, Karnataka, IndiaDepartment of Pharmaceutical Chemistry, Sree Siddaganga College of Pharmacy, B.H.Road, Tumkur-572102, Karnataka, IndiaSome new chalcones have been synthesized by the condensation of 2-acetyl thiophene with various aromatic aldehydes in 40% alkali. The synthesized compounds were identified by spectral data and screened for anti-inflammatory activity. Some of these compounds showed moderate to considerable anti-inflammatory activity.http://dx.doi.org/10.1155/2010/404715
spellingShingle B. Ramesh
B. Someswara Rao
Synthesis, Spectral Studies and Anti-Inflammatory Activity of 2-Acetyl Thiophene
E-Journal of Chemistry
title Synthesis, Spectral Studies and Anti-Inflammatory Activity of 2-Acetyl Thiophene
title_full Synthesis, Spectral Studies and Anti-Inflammatory Activity of 2-Acetyl Thiophene
title_fullStr Synthesis, Spectral Studies and Anti-Inflammatory Activity of 2-Acetyl Thiophene
title_full_unstemmed Synthesis, Spectral Studies and Anti-Inflammatory Activity of 2-Acetyl Thiophene
title_short Synthesis, Spectral Studies and Anti-Inflammatory Activity of 2-Acetyl Thiophene
title_sort synthesis spectral studies and anti inflammatory activity of 2 acetyl thiophene
url http://dx.doi.org/10.1155/2010/404715
work_keys_str_mv AT bramesh synthesisspectralstudiesandantiinflammatoryactivityof2acetylthiophene
AT bsomeswararao synthesisspectralstudiesandantiinflammatoryactivityof2acetylthiophene