Nomogram to screen older adult patients attending the radiology department for sarcopenia
Abstract Background Sarcopenia is an age-related syndrome that can impact the physical and mental health of older adults. However, it is often overlooked in clinical practice. Therefore, we aim to construct a nomogram based on simplified discriminant parameters for screening older adult patients for...
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BMC
2025-01-01
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| Series: | BMC Geriatrics |
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| Online Access: | https://doi.org/10.1186/s12877-025-05730-1 |
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| author | Guiying Yuan Guoxi Ye Jianguang Hu Huimin Hu Chanmei Shi Ye Zhang Junbing Huang Zhiqiong Li Xuwen Zeng Rongshao Tan Yuchao Xiong |
| author_facet | Guiying Yuan Guoxi Ye Jianguang Hu Huimin Hu Chanmei Shi Ye Zhang Junbing Huang Zhiqiong Li Xuwen Zeng Rongshao Tan Yuchao Xiong |
| author_sort | Guiying Yuan |
| collection | DOAJ |
| description | Abstract Background Sarcopenia is an age-related syndrome that can impact the physical and mental health of older adults. However, it is often overlooked in clinical practice. Therefore, we aim to construct a nomogram based on simplified discriminant parameters for screening older adult patients for sarcopenia risk. Methods This cross-sectional study included 654 patients aged ≥ 60 years who underwent an examination in the radiology department between October 2023 and June 2024. Patients were diagnosed with sarcopenia according to the method and cutoff value criteria proposed the Asian Working Group on Sarcopenia (AWGS) 2019 criteria. Calf circumference (CC), SARC-F score, mid-upper arm circumference (MUAC), and SARC-CalF score were used as simplified discriminant parameters for sarcopenia. The discriminative ability of these parameters for sarcopenia was assessed using receiver operating characteristic analysis. Additionally, we included each screening parameter and evaluated it’s important for screening for the presence of sarcopenia via univariate and multivariate logistic regression analysis to develop a new screening nomogram model. The performance of the nomogram was evaluated using receiver operating characteristic curves, and the performance of the nomogram model was compared to that of CC, SARC-F, MUAC, and the SARC-CalF using the Delong test. Results Of the 654 subjects, 120 (18.3%) were diagnosed with sarcopenia, and the areas under the curve (AUCs) of the CC, SARC-F, MUAC, and SARC-CalF were 0.73, 0.61, 0.66, and 0.70, respectively. The multivariate analysis results revealed that older age, male sex, low CC, low MUAC, and low strength were related to sarcopenia. A nomogram model constructed with these five variables had an AUC of 0.84. The DeLong test showed that the diagnostic efficacy of the joint model was significantly higher than that of CC, SARC-F, MUAC, and SARC-CalF. Conclusions Our simple nomogram based on simplified discriminant parameters offers personalized sarcopenia screening for older adult patients attending the radiology department. |
| format | Article |
| id | doaj-art-99f06c2327e04e0797708bfe3c6d6f88 |
| institution | Kabale University |
| issn | 1471-2318 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj-art-99f06c2327e04e0797708bfe3c6d6f882025-02-02T12:41:45ZengBMCBMC Geriatrics1471-23182025-01-012511910.1186/s12877-025-05730-1Nomogram to screen older adult patients attending the radiology department for sarcopeniaGuiying Yuan0Guoxi Ye1Jianguang Hu2Huimin Hu3Chanmei Shi4Ye Zhang5Junbing Huang6Zhiqiong Li7Xuwen Zeng8Rongshao Tan9Yuchao Xiong10Department of Respiratory, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Department of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Department of Nephrology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Department of Nephrology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Department of Respiratory, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Department of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Department of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Department of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Department of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Department of Clinical Nutrition, Institute of Disease-Oriented Nutritional Research, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Department of Radiology, Guangzhou Red Cross Hospital (Guangzhou Red Cross Hospital of Jinan University)Abstract Background Sarcopenia is an age-related syndrome that can impact the physical and mental health of older adults. However, it is often overlooked in clinical practice. Therefore, we aim to construct a nomogram based on simplified discriminant parameters for screening older adult patients for sarcopenia risk. Methods This cross-sectional study included 654 patients aged ≥ 60 years who underwent an examination in the radiology department between October 2023 and June 2024. Patients were diagnosed with sarcopenia according to the method and cutoff value criteria proposed the Asian Working Group on Sarcopenia (AWGS) 2019 criteria. Calf circumference (CC), SARC-F score, mid-upper arm circumference (MUAC), and SARC-CalF score were used as simplified discriminant parameters for sarcopenia. The discriminative ability of these parameters for sarcopenia was assessed using receiver operating characteristic analysis. Additionally, we included each screening parameter and evaluated it’s important for screening for the presence of sarcopenia via univariate and multivariate logistic regression analysis to develop a new screening nomogram model. The performance of the nomogram was evaluated using receiver operating characteristic curves, and the performance of the nomogram model was compared to that of CC, SARC-F, MUAC, and the SARC-CalF using the Delong test. Results Of the 654 subjects, 120 (18.3%) were diagnosed with sarcopenia, and the areas under the curve (AUCs) of the CC, SARC-F, MUAC, and SARC-CalF were 0.73, 0.61, 0.66, and 0.70, respectively. The multivariate analysis results revealed that older age, male sex, low CC, low MUAC, and low strength were related to sarcopenia. A nomogram model constructed with these five variables had an AUC of 0.84. The DeLong test showed that the diagnostic efficacy of the joint model was significantly higher than that of CC, SARC-F, MUAC, and SARC-CalF. Conclusions Our simple nomogram based on simplified discriminant parameters offers personalized sarcopenia screening for older adult patients attending the radiology department.https://doi.org/10.1186/s12877-025-05730-1SarcopeniaNomogramCalf circumferenceSARC-FSARC-CalF |
| spellingShingle | Guiying Yuan Guoxi Ye Jianguang Hu Huimin Hu Chanmei Shi Ye Zhang Junbing Huang Zhiqiong Li Xuwen Zeng Rongshao Tan Yuchao Xiong Nomogram to screen older adult patients attending the radiology department for sarcopenia BMC Geriatrics Sarcopenia Nomogram Calf circumference SARC-F SARC-CalF |
| title | Nomogram to screen older adult patients attending the radiology department for sarcopenia |
| title_full | Nomogram to screen older adult patients attending the radiology department for sarcopenia |
| title_fullStr | Nomogram to screen older adult patients attending the radiology department for sarcopenia |
| title_full_unstemmed | Nomogram to screen older adult patients attending the radiology department for sarcopenia |
| title_short | Nomogram to screen older adult patients attending the radiology department for sarcopenia |
| title_sort | nomogram to screen older adult patients attending the radiology department for sarcopenia |
| topic | Sarcopenia Nomogram Calf circumference SARC-F SARC-CalF |
| url | https://doi.org/10.1186/s12877-025-05730-1 |
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