Associations of Blood Lipids with the Risk and Prognosis of Sudden Sensorineural Hearing Loss: A Meta-analysis
Bacground: Patients with sudden sensorineural hearing loss (SSNHL) may lose their hearing. The relationship between SSNHL and total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) levels is still unclear. The associat...
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| Format: | Article |
| Language: | English |
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AVES
2024-09-01
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| Series: | Journal of International Advanced Otology |
| Online Access: | https://www.advancedotology.org/en/associations-of-blood-lipids-with-the-risk-and-prognosis-of-sudden-sensorineural-hearing-loss-a-meta-analysis-131958 |
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| _version_ | 1832557184623312896 |
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| author | Jie Li Yong-Ming Zhu Ya-Qin Wang Xiao-Chun Gu |
| author_facet | Jie Li Yong-Ming Zhu Ya-Qin Wang Xiao-Chun Gu |
| author_sort | Jie Li |
| collection | DOAJ |
| description | Bacground: Patients with sudden sensorineural hearing loss (SSNHL) may lose their hearing. The relationship between SSNHL and total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) levels is still unclear. The association of TC, TG, HDL-C, and LDL-C levels with the risk and prognosis of SSNHL was explored in this study.
Methods: After searching for literature in different databases, 13 researches were used to summarize the risk and prognosis of SSNHL associations with TC, TG, HDL-C, and LDL-C using meta-analysis.
Results: Total cholesterol had a significant association with the risk of SSNHL (95% CI, 1.34-2.91). Adjustment for confounding factors and grouping criteria of TG were all significant sources of heterogeneity. One of the significant sources of heterogeneity in the LDL-C subgroup analyses was an adjustment for confounders. Sensitivity analysis revealed a robust association between TC and the risk of SSNHL. There was a significant publication bias in the association between TC and SSNHL prognosis
Conclusion: High TC level is a risk factor for SSNHL. |
| format | Article |
| id | doaj-art-99e92f05d4904a9db012f30f4b2c1b10 |
| institution | Kabale University |
| issn | 2148-3817 |
| language | English |
| publishDate | 2024-09-01 |
| publisher | AVES |
| record_format | Article |
| series | Journal of International Advanced Otology |
| spelling | doaj-art-99e92f05d4904a9db012f30f4b2c1b102025-02-03T05:38:12ZengAVESJournal of International Advanced Otology2148-38172024-09-0120543143810.5152/iao.2024.241601Associations of Blood Lipids with the Risk and Prognosis of Sudden Sensorineural Hearing Loss: A Meta-analysisJie Li0Yong-Ming Zhu1Ya-Qin Wang2Xiao-Chun Gu3Department of Otolaryngology, Nantong Hospital of Traditional Chinese Medicine, Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Nantong, Jiangsu, ChinaDepartment of Otolaryngology, Nantong Hospital of Traditional Chinese Medicine, Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Nantong, Jiangsu, ChinaDepartment of Otolaryngology, Nantong Hospital of Traditional Chinese Medicine, Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Nantong, Jiangsu, ChinaDepartment of Otolaryngology, Nantong Hospital of Traditional Chinese Medicine, Nantong Hospital Affiliated to Nanjing University of Chinese Medicine, Nantong, Jiangsu, ChinaBacground: Patients with sudden sensorineural hearing loss (SSNHL) may lose their hearing. The relationship between SSNHL and total cholesterol (TC), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), and low-density lipoprotein cholesterol (LDL-C) levels is still unclear. The association of TC, TG, HDL-C, and LDL-C levels with the risk and prognosis of SSNHL was explored in this study. Methods: After searching for literature in different databases, 13 researches were used to summarize the risk and prognosis of SSNHL associations with TC, TG, HDL-C, and LDL-C using meta-analysis. Results: Total cholesterol had a significant association with the risk of SSNHL (95% CI, 1.34-2.91). Adjustment for confounding factors and grouping criteria of TG were all significant sources of heterogeneity. One of the significant sources of heterogeneity in the LDL-C subgroup analyses was an adjustment for confounders. Sensitivity analysis revealed a robust association between TC and the risk of SSNHL. There was a significant publication bias in the association between TC and SSNHL prognosis Conclusion: High TC level is a risk factor for SSNHL.https://www.advancedotology.org/en/associations-of-blood-lipids-with-the-risk-and-prognosis-of-sudden-sensorineural-hearing-loss-a-meta-analysis-131958 |
| spellingShingle | Jie Li Yong-Ming Zhu Ya-Qin Wang Xiao-Chun Gu Associations of Blood Lipids with the Risk and Prognosis of Sudden Sensorineural Hearing Loss: A Meta-analysis Journal of International Advanced Otology |
| title | Associations of Blood Lipids with the Risk and Prognosis of Sudden Sensorineural Hearing Loss: A Meta-analysis |
| title_full | Associations of Blood Lipids with the Risk and Prognosis of Sudden Sensorineural Hearing Loss: A Meta-analysis |
| title_fullStr | Associations of Blood Lipids with the Risk and Prognosis of Sudden Sensorineural Hearing Loss: A Meta-analysis |
| title_full_unstemmed | Associations of Blood Lipids with the Risk and Prognosis of Sudden Sensorineural Hearing Loss: A Meta-analysis |
| title_short | Associations of Blood Lipids with the Risk and Prognosis of Sudden Sensorineural Hearing Loss: A Meta-analysis |
| title_sort | associations of blood lipids with the risk and prognosis of sudden sensorineural hearing loss a meta analysis |
| url | https://www.advancedotology.org/en/associations-of-blood-lipids-with-the-risk-and-prognosis-of-sudden-sensorineural-hearing-loss-a-meta-analysis-131958 |
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