Transmission of transgenic mosquito-killing fungi during copulation
Abstract Entomopathogenic fungi engineered to express insect-specific neurotoxins have demonstrated potential as microbial control agents against malaria mosquitoes. Currently, the primary application method is via direct contact of spores with indoor resting mosquitoes. However, many malaria-transm...
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-024-83242-5 |
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| author | Etienne Bilgo Brian Lovett Abel Souro Millogo Issiaka Sare Edounou Jacques Gnambani Raymond St. Leger Abdoulaye Diabaté |
| author_facet | Etienne Bilgo Brian Lovett Abel Souro Millogo Issiaka Sare Edounou Jacques Gnambani Raymond St. Leger Abdoulaye Diabaté |
| author_sort | Etienne Bilgo |
| collection | DOAJ |
| description | Abstract Entomopathogenic fungi engineered to express insect-specific neurotoxins have demonstrated potential as microbial control agents against malaria mosquitoes. Currently, the primary application method is via direct contact of spores with indoor resting mosquitoes. However, many malaria-transmitting mosquitoes feed and rest outdoors. To target these, we have developed an alternative application method that exploits the lethality of transgenic fungi as a sexually transmitted mosquito disease. This approach has both a wider interdisciplinary significance and important implications for preventing mosquito-borne diseases. |
| format | Article |
| id | doaj-art-99e01f2d1744449fbb6a6770d52ae18f |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-99e01f2d1744449fbb6a6770d52ae18f2025-01-19T12:20:44ZengNature PortfolioScientific Reports2045-23222025-01-011511410.1038/s41598-024-83242-5Transmission of transgenic mosquito-killing fungi during copulationEtienne Bilgo0Brian Lovett1Abel Souro Millogo2Issiaka Sare3Edounou Jacques Gnambani4Raymond St. Leger5Abdoulaye Diabaté6Institut de Recherche en Sciences de la Santé, IRSSUnited States Department of Agriculture Research ServiceInstitut de Recherche en Sciences de la Santé, IRSSInstitut de Recherche en Sciences de la Santé, IRSSInstitut de Recherche en Sciences de la Santé, IRSSUniversity of MarylandInstitut de Recherche en Sciences de la Santé, IRSSAbstract Entomopathogenic fungi engineered to express insect-specific neurotoxins have demonstrated potential as microbial control agents against malaria mosquitoes. Currently, the primary application method is via direct contact of spores with indoor resting mosquitoes. However, many malaria-transmitting mosquitoes feed and rest outdoors. To target these, we have developed an alternative application method that exploits the lethality of transgenic fungi as a sexually transmitted mosquito disease. This approach has both a wider interdisciplinary significance and important implications for preventing mosquito-borne diseases.https://doi.org/10.1038/s41598-024-83242-5 |
| spellingShingle | Etienne Bilgo Brian Lovett Abel Souro Millogo Issiaka Sare Edounou Jacques Gnambani Raymond St. Leger Abdoulaye Diabaté Transmission of transgenic mosquito-killing fungi during copulation Scientific Reports |
| title | Transmission of transgenic mosquito-killing fungi during copulation |
| title_full | Transmission of transgenic mosquito-killing fungi during copulation |
| title_fullStr | Transmission of transgenic mosquito-killing fungi during copulation |
| title_full_unstemmed | Transmission of transgenic mosquito-killing fungi during copulation |
| title_short | Transmission of transgenic mosquito-killing fungi during copulation |
| title_sort | transmission of transgenic mosquito killing fungi during copulation |
| url | https://doi.org/10.1038/s41598-024-83242-5 |
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