2019-nCoV Transmission in Hubei Province, China: Stochastic and Deterministic Analyses

Currently, a novel coronavirus (2019-nCoV) causes an outbreak of viral pneumonia in Hubei province, China. In this paper, stochastic and deterministic models are proposed to investigate the transmission mechanism of 2019-nCoV from 15 January to 5 February 2020 in Hubei province. For the deterministi...

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Main Authors: Zhiming Li, Zhidong Teng, Changxing Ma
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Complexity
Online Access:http://dx.doi.org/10.1155/2020/9012178
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author Zhiming Li
Zhidong Teng
Changxing Ma
author_facet Zhiming Li
Zhidong Teng
Changxing Ma
author_sort Zhiming Li
collection DOAJ
description Currently, a novel coronavirus (2019-nCoV) causes an outbreak of viral pneumonia in Hubei province, China. In this paper, stochastic and deterministic models are proposed to investigate the transmission mechanism of 2019-nCoV from 15 January to 5 February 2020 in Hubei province. For the deterministic model, basic reproduction number R0 is defined and endemic equilibrium is given. Under R0>1, quasi-stationary distribution of the stochastic process is approximated by Gaussian diffusion. Residual, sensitivity, dynamical, and diffusion analyses of the models are conducted. Further, control variables are introduced to the deterministic model and optimal strategies are provided. Based on empirical results, we suggest that the first and most important thing is to control input, screening, treatment, and isolation.
format Article
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institution Kabale University
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publishDate 2020-01-01
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series Complexity
spelling doaj-art-99dd1435373542f39bbb86c50ee349c72025-02-03T05:52:28ZengWileyComplexity1076-27871099-05262020-01-01202010.1155/2020/901217890121782019-nCoV Transmission in Hubei Province, China: Stochastic and Deterministic AnalysesZhiming Li0Zhidong Teng1Changxing Ma2College of Mathematics and System Sciences, Xinjiang University, Urumqi 834800, ChinaCollege of Mathematics and System Sciences, Xinjiang University, Urumqi 834800, ChinaDepartment of Biostatistics, University at Buffalo, Buffalo 14214, USACurrently, a novel coronavirus (2019-nCoV) causes an outbreak of viral pneumonia in Hubei province, China. In this paper, stochastic and deterministic models are proposed to investigate the transmission mechanism of 2019-nCoV from 15 January to 5 February 2020 in Hubei province. For the deterministic model, basic reproduction number R0 is defined and endemic equilibrium is given. Under R0>1, quasi-stationary distribution of the stochastic process is approximated by Gaussian diffusion. Residual, sensitivity, dynamical, and diffusion analyses of the models are conducted. Further, control variables are introduced to the deterministic model and optimal strategies are provided. Based on empirical results, we suggest that the first and most important thing is to control input, screening, treatment, and isolation.http://dx.doi.org/10.1155/2020/9012178
spellingShingle Zhiming Li
Zhidong Teng
Changxing Ma
2019-nCoV Transmission in Hubei Province, China: Stochastic and Deterministic Analyses
Complexity
title 2019-nCoV Transmission in Hubei Province, China: Stochastic and Deterministic Analyses
title_full 2019-nCoV Transmission in Hubei Province, China: Stochastic and Deterministic Analyses
title_fullStr 2019-nCoV Transmission in Hubei Province, China: Stochastic and Deterministic Analyses
title_full_unstemmed 2019-nCoV Transmission in Hubei Province, China: Stochastic and Deterministic Analyses
title_short 2019-nCoV Transmission in Hubei Province, China: Stochastic and Deterministic Analyses
title_sort 2019 ncov transmission in hubei province china stochastic and deterministic analyses
url http://dx.doi.org/10.1155/2020/9012178
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AT zhidongteng 2019ncovtransmissioninhubeiprovincechinastochasticanddeterministicanalyses
AT changxingma 2019ncovtransmissioninhubeiprovincechinastochasticanddeterministicanalyses