Interindividual Variability Response to Resistance and High-Intensity Interval Training on Blood Pressure Reduction in Hypertensive Older Adults

Background: This study evaluated the effects of resistance training (RT) and high-intensity interval training (HIIT) on systolic (SBP) and diastolic blood pressure (DBP) in hypertensive older adults undergoing pharmacological therapy over four and eight weeks. We compared the efficacy of RT and HIIT...

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Main Authors: Johnattan Cano-Montoya, Nicolas Hurtado, Carolina Núñez Vergara, Sebastián Báez Vargas, Marcela Rojas-Vargas, Sergio Martínez-Huenchullán, Cristian Alvarez, Mikel Izquierdo
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Journal of Cardiovascular Development and Disease
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Online Access:https://www.mdpi.com/2308-3425/12/1/30
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author Johnattan Cano-Montoya
Nicolas Hurtado
Carolina Núñez Vergara
Sebastián Báez Vargas
Marcela Rojas-Vargas
Sergio Martínez-Huenchullán
Cristian Alvarez
Mikel Izquierdo
author_facet Johnattan Cano-Montoya
Nicolas Hurtado
Carolina Núñez Vergara
Sebastián Báez Vargas
Marcela Rojas-Vargas
Sergio Martínez-Huenchullán
Cristian Alvarez
Mikel Izquierdo
author_sort Johnattan Cano-Montoya
collection DOAJ
description Background: This study evaluated the effects of resistance training (RT) and high-intensity interval training (HIIT) on systolic (SBP) and diastolic blood pressure (DBP) in hypertensive older adults undergoing pharmacological therapy over four and eight weeks. We compared the efficacy of RT and HIIT in reducing non-responders (NRs) between weeks 4 and 8 and analyzed time-course adaptations in NRs and responders (Rs). Methods: Thirty-nine participants were randomized into RT-G (<i>n</i> = 13), HIIT-G (<i>n</i> = 13), or control (CG, <i>n</i> = 13) groups. RT utilized elastic bands, and HIIT involved cycle ergometers, with three weekly 30 min sessions for 8 weeks. SBP and DBP were measured before intervention and at weeks 4 and 8, respectively. Individual responses were classified as NRs or Rs using the Hopkins method (SDIR = √[SDExp2–SDCon2]). Time-course adaptations were evaluated. Results: Both the RT-G and HIIT-G reduced SBP at 8 weeks (RT-G: −13 mmHg; [ES: 1.12]; HIIT-G: −12 mmHg [ES: 0.8]; both <i>p</i> < 0.05). The proportion of NRs for SBP decreased from 46% to 38% in RT-G and 69% to 46% in HIIT-G. Rs showed a peak SBP reduction at 4 weeks (−14.7 and −25.5 mmHg), stabilizing by week 8 (−22.8 and −19.6 mmHg) in RT-G and HIIT-G, respectively. Conclusion: Eight weeks of RT and HIIT effectively reduced SBP and NR prevalence, with time-course adaptations favoring Rs.
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spelling doaj-art-99dc1f9d69c14248aa9eb55feab254fd2025-01-24T13:36:03ZengMDPI AGJournal of Cardiovascular Development and Disease2308-34252025-01-011213010.3390/jcdd12010030Interindividual Variability Response to Resistance and High-Intensity Interval Training on Blood Pressure Reduction in Hypertensive Older AdultsJohnattan Cano-Montoya0Nicolas Hurtado1Carolina Núñez Vergara2Sebastián Báez Vargas3Marcela Rojas-Vargas4Sergio Martínez-Huenchullán5Cristian Alvarez6Mikel Izquierdo7School of Kinesiology, Faculty of Dentistry and Rehabilitation Sciences, Universidad San Sebastián, Valdivia 5090000, ChileSchool of Kinesiology, Faculty of Dentistry and Rehabilitation Sciences, Universidad San Sebastián, Valdivia 5090000, ChileSchool of Kinesiology, Faculty of Dentistry and Rehabilitation Sciences, Universidad San Sebastián, Valdivia 5090000, ChileSchool of Kinesiology, Faculty of Dentistry and Rehabilitation Sciences, Universidad San Sebastián, Valdivia 5090000, ChileSchool of Kinesiology, Faculty of Dentistry and Rehabilitation Sciences, Universidad San Sebastián, Valdivia 5090000, ChileSchool of Kinesiology, Faculty of Dentistry and Rehabilitation Sciences, Universidad San Sebastián, Valdivia 5090000, ChileExercise and Rehabilitation Sciences Institute, School of Physical Therapy, Faculty of Rehabilitation Sciences, Universidad Andres Bello, Santiago 7591538, ChileNavarrabiomed, Hospital Universitario de Navarra (HUN), Universidad Pública de Navarra (UPNA), IdiSNA, 31006 Pamplona, SpainBackground: This study evaluated the effects of resistance training (RT) and high-intensity interval training (HIIT) on systolic (SBP) and diastolic blood pressure (DBP) in hypertensive older adults undergoing pharmacological therapy over four and eight weeks. We compared the efficacy of RT and HIIT in reducing non-responders (NRs) between weeks 4 and 8 and analyzed time-course adaptations in NRs and responders (Rs). Methods: Thirty-nine participants were randomized into RT-G (<i>n</i> = 13), HIIT-G (<i>n</i> = 13), or control (CG, <i>n</i> = 13) groups. RT utilized elastic bands, and HIIT involved cycle ergometers, with three weekly 30 min sessions for 8 weeks. SBP and DBP were measured before intervention and at weeks 4 and 8, respectively. Individual responses were classified as NRs or Rs using the Hopkins method (SDIR = √[SDExp2–SDCon2]). Time-course adaptations were evaluated. Results: Both the RT-G and HIIT-G reduced SBP at 8 weeks (RT-G: −13 mmHg; [ES: 1.12]; HIIT-G: −12 mmHg [ES: 0.8]; both <i>p</i> < 0.05). The proportion of NRs for SBP decreased from 46% to 38% in RT-G and 69% to 46% in HIIT-G. Rs showed a peak SBP reduction at 4 weeks (−14.7 and −25.5 mmHg), stabilizing by week 8 (−22.8 and −19.6 mmHg) in RT-G and HIIT-G, respectively. Conclusion: Eight weeks of RT and HIIT effectively reduced SBP and NR prevalence, with time-course adaptations favoring Rs.https://www.mdpi.com/2308-3425/12/1/30exercisehypertensioninter-individual variabilityolder adults
spellingShingle Johnattan Cano-Montoya
Nicolas Hurtado
Carolina Núñez Vergara
Sebastián Báez Vargas
Marcela Rojas-Vargas
Sergio Martínez-Huenchullán
Cristian Alvarez
Mikel Izquierdo
Interindividual Variability Response to Resistance and High-Intensity Interval Training on Blood Pressure Reduction in Hypertensive Older Adults
Journal of Cardiovascular Development and Disease
exercise
hypertension
inter-individual variability
older adults
title Interindividual Variability Response to Resistance and High-Intensity Interval Training on Blood Pressure Reduction in Hypertensive Older Adults
title_full Interindividual Variability Response to Resistance and High-Intensity Interval Training on Blood Pressure Reduction in Hypertensive Older Adults
title_fullStr Interindividual Variability Response to Resistance and High-Intensity Interval Training on Blood Pressure Reduction in Hypertensive Older Adults
title_full_unstemmed Interindividual Variability Response to Resistance and High-Intensity Interval Training on Blood Pressure Reduction in Hypertensive Older Adults
title_short Interindividual Variability Response to Resistance and High-Intensity Interval Training on Blood Pressure Reduction in Hypertensive Older Adults
title_sort interindividual variability response to resistance and high intensity interval training on blood pressure reduction in hypertensive older adults
topic exercise
hypertension
inter-individual variability
older adults
url https://www.mdpi.com/2308-3425/12/1/30
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