The critical role of PDGFRa + Sca1 + fibroblasts in angiogenesis and vascular repair in the corpus cavernosum

The critical role of PDGFRa + Sca1 + fibroblasts in angiogenesis and vascular repair in the corpus cavernosum

Abstract Background Erectile dysfunction (ED) is an important cause of reduced quality of life for men and their partners. A common pathological feature across various types of ED, including diabetes mellitus-induced ED (DMED) and bilateral cavernous nerve injury-induced ED (CNIED), is the loss of e...

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Main Authors: Biao Liu, Zitaiyu Li, Zhitao Han, Yuzhuo Chen, Yanghua Xu, Jiarong Xu, Hongji Hu, Ningjing Ou, Xiaoping Zheng, Yinghao Yin, Dongyi Peng, Liangyu Zhao, Yuxin Tang
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Stem Cell Research & Therapy
Subjects:
Erectile dysfunction
Single-cell transcriptome
Fibroblast
Stem cell
Online Access:https://doi.org/10.1186/s13287-025-04434-y
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