miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding
It has been shown that miR-145 is involved in the differentiation of vascular smooth muscle cells (VSMCs) and may regulate vascular remodeling. However, the molecular mechanisms behind these pathological processes in hypertension are not fully elucidated. The present study was to examine whether miR...
Saved in:
Main Authors: | Juan Wen, Baiyi Tang, Lan Guo, Wei Chen, Xiaohong Tang |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2023-01-01
|
Series: | International Journal of Hypertension |
Online Access: | http://dx.doi.org/10.1155/2023/9497716 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Evidence That ADAM17 Mediates the Protective Action of CGRP against Angiotensin II-Induced Inflammation in Vascular Smooth Muscle Cells
by: Si-yu Zeng, et al.
Published: (2018-01-01) -
Salvianolic Acid B Alleviates High Glucose-Induced Vascular Smooth Muscle Cell Inflammation by Upregulating the miR-486a-5p Expression
by: Man-Li Zhang, et al.
Published: (2024-01-01) -
miR-26a-5p/ADAM17-Mediated Proteolysis of TREM2 Regulates Neuroinflammation in Hypertensive Mice Following Lead Exposure
by: Yuran Wang, et al.
Published: (2025-01-01) -
circCOL1A1 Promotes the Progression of Gastric Cancer Cells through Sponging miR-145 to Enhance RABL3 Expression
by: Yue Ma, et al.
Published: (2021-01-01) -
Phenotypic and Functional Changes of Endothelial and Smooth Muscle Cells in Thoracic Aortic Aneurysms
by: Anna Malashicheva, et al.
Published: (2016-01-01)