Discrete Immolative Guanidinium Transporters deliver mRNA to specific organs and red blood cells
Abstract RNA medicine is an emerging groundbreaking technology for the prevention and treatment of disease. However, tools to deliver messenger RNA (mRNA) and other polyanions (circRNA, saRNA, pDNA, CRISPR-Cas, reprogramming factors) are required to advance current RNA therapies and address next gen...
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| Main Authors: | Zhijian Li, Aloysius Ee, Laura Amaya, Jennifer L. Hamad, Pavan K. Yadav, Sean K. Wang, Howard Y. Chang, Paul A. Wender |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-08-01
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| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-62200-3 |
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