Elevated SAMD3 expression in T cells predicts improved survival in pancreatic ductal adenocarcinoma patients
Abstract Objective Pancreatic ductal adenocarcinoma (PDAC) has an immune-suppressive tumor microenvironment that contributes to resistance to immunotherapy. This study aimed to demonstrate that elevated sterile alpha motif domain-containing protein 3 (SAMD3) expression in effector CD8+ T cells was a...
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Main Authors: | Lingyi Fu, Enliang Zhou, Shuo Li, Ziteng Li, Liyan Wu, Xinxin Zhou, Lang Tian, Bokang Cui |
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Format: | Article |
Language: | English |
Published: |
Springer
2025-02-01
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Series: | Cancer Immunology, Immunotherapy |
Subjects: | |
Online Access: | https://doi.org/10.1007/s00262-025-03948-x |
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