Comparison of macular retinal thickness measurements using spectral-domain and swept-source optical coherence tomography in healthy eyes
AimThis study compares retinal thickness measurements in healthy eyes using one SD-OCT and two SS-OCT devices to assess differences and consistency for clinical application.MethodsForty-eight eyes with a mean age of 28.15 ± 8.85 years were enrolled. Retinal thickness was measured using Heidelberg Sp...
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Frontiers Media S.A.
2025-01-01
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1529719/full |
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| author | Huan Wan Zhaode Wu Ziling Liu Bo Qin |
| author_facet | Huan Wan Zhaode Wu Ziling Liu Bo Qin |
| author_sort | Huan Wan |
| collection | DOAJ |
| description | AimThis study compares retinal thickness measurements in healthy eyes using one SD-OCT and two SS-OCT devices to assess differences and consistency for clinical application.MethodsForty-eight eyes with a mean age of 28.15 ± 8.85 years were enrolled. Retinal thickness was measured using Heidelberg Spectralis SD-OCT, Svision VG200 SS-OCT, and TowardPi En Face SS-OCT. Normally distributed data were presented as mean ± SD; non-normal data as median (P25–P75). Intraclass correlation coefficients (ICC) and Bland–Altman analysis were used to assess agreement, with a 7 μm error threshold.ResultsSignificant differences were found between the three devices (p < 0.001). SD-OCT measurements were consistently lower than SS-OCT (p < 0.001), while the two SS-OCT devices showed no significant differences except in the nasal region (p = 0.006). ICC values between SD-OCT and SS-OCT devices were low (0.125–0.532), while SS-OCT devices showed better agreement (ICC: 0.369–0.922). Bland–Altman analysis found only 8.33% of SD-OCT and SS-OCT measurements within the 7 μm error range, compared to 81.25–83.33% for SS-OCT devices.ConclusionThe measurements of macular retinal thickness using SD-OCT and SS-OCT devices showed poor consistency and cannot be used interchangeably. However, measurements obtained from different SS-OCT devices demonstrated good consistency. To enhance the accuracy of results, it is recommended to maintain consistency in the devices used for follow-up examinations in the same patient. |
| format | Article |
| id | doaj-art-99a97f13a22e40d79da2c26dfbb2f837 |
| institution | Kabale University |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Medicine |
| spelling | doaj-art-99a97f13a22e40d79da2c26dfbb2f8372025-01-31T06:39:48ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-01-011210.3389/fmed.2025.15297191529719Comparison of macular retinal thickness measurements using spectral-domain and swept-source optical coherence tomography in healthy eyesHuan Wan0Zhaode Wu1Ziling Liu2Bo Qin3The Second Clinical Medical College of Jinan University, Shenzhen, ChinaDepartment of Ophthalmology, Shenzhen People’s Hospital, The Second Clinical Medical College of Jinan University, Shenzhen, Guangdong, ChinaShenzhen Aier Eye Hospital, Aier Eye Hospital, Jinan University, Shenzhen, ChinaShenzhen Aier Eye Hospital, Aier Eye Hospital, Jinan University, Shenzhen, ChinaAimThis study compares retinal thickness measurements in healthy eyes using one SD-OCT and two SS-OCT devices to assess differences and consistency for clinical application.MethodsForty-eight eyes with a mean age of 28.15 ± 8.85 years were enrolled. Retinal thickness was measured using Heidelberg Spectralis SD-OCT, Svision VG200 SS-OCT, and TowardPi En Face SS-OCT. Normally distributed data were presented as mean ± SD; non-normal data as median (P25–P75). Intraclass correlation coefficients (ICC) and Bland–Altman analysis were used to assess agreement, with a 7 μm error threshold.ResultsSignificant differences were found between the three devices (p < 0.001). SD-OCT measurements were consistently lower than SS-OCT (p < 0.001), while the two SS-OCT devices showed no significant differences except in the nasal region (p = 0.006). ICC values between SD-OCT and SS-OCT devices were low (0.125–0.532), while SS-OCT devices showed better agreement (ICC: 0.369–0.922). Bland–Altman analysis found only 8.33% of SD-OCT and SS-OCT measurements within the 7 μm error range, compared to 81.25–83.33% for SS-OCT devices.ConclusionThe measurements of macular retinal thickness using SD-OCT and SS-OCT devices showed poor consistency and cannot be used interchangeably. However, measurements obtained from different SS-OCT devices demonstrated good consistency. To enhance the accuracy of results, it is recommended to maintain consistency in the devices used for follow-up examinations in the same patient.https://www.frontiersin.org/articles/10.3389/fmed.2025.1529719/fulloptical coherence tomography (OCT)spectral-domain OCT (SD-OCT)swept-source OCT (SS-OCT)retinal thickness measurementconsistency analysis |
| spellingShingle | Huan Wan Zhaode Wu Ziling Liu Bo Qin Comparison of macular retinal thickness measurements using spectral-domain and swept-source optical coherence tomography in healthy eyes Frontiers in Medicine optical coherence tomography (OCT) spectral-domain OCT (SD-OCT) swept-source OCT (SS-OCT) retinal thickness measurement consistency analysis |
| title | Comparison of macular retinal thickness measurements using spectral-domain and swept-source optical coherence tomography in healthy eyes |
| title_full | Comparison of macular retinal thickness measurements using spectral-domain and swept-source optical coherence tomography in healthy eyes |
| title_fullStr | Comparison of macular retinal thickness measurements using spectral-domain and swept-source optical coherence tomography in healthy eyes |
| title_full_unstemmed | Comparison of macular retinal thickness measurements using spectral-domain and swept-source optical coherence tomography in healthy eyes |
| title_short | Comparison of macular retinal thickness measurements using spectral-domain and swept-source optical coherence tomography in healthy eyes |
| title_sort | comparison of macular retinal thickness measurements using spectral domain and swept source optical coherence tomography in healthy eyes |
| topic | optical coherence tomography (OCT) spectral-domain OCT (SD-OCT) swept-source OCT (SS-OCT) retinal thickness measurement consistency analysis |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1529719/full |
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