Transcriptome Analyses Reveal Lipid Metabolic Process in Liver Related to the Difference of Carcass Fat Content in Rainbow Trout (Oncorhynchus mykiss)
Excessive accumulation of carcass fat in farm animals, including fish, has a significant impact on meat quality and on the cost of feeding. Similar to farmed animals and humans, the liver can be considered one of the most important organs involved in lipid metabolism in rainbow trout (Oncorhynchus m...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | International Journal of Genomics |
| Online Access: | http://dx.doi.org/10.1155/2016/7281585 |
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| _version_ | 1832552375647207424 |
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| author | Guo Hu Wei Gu Peng Sun Qingli Bai Bingqian Wang |
| author_facet | Guo Hu Wei Gu Peng Sun Qingli Bai Bingqian Wang |
| author_sort | Guo Hu |
| collection | DOAJ |
| description | Excessive accumulation of carcass fat in farm animals, including fish, has a significant impact on meat quality and on the cost of feeding. Similar to farmed animals and humans, the liver can be considered one of the most important organs involved in lipid metabolism in rainbow trout (Oncorhynchus mykiss). RNA-seq based whole transcriptome sequencing was performed to liver tissue of rainbow trout with high and low carcass fat content in this study. In total 1,694 differentially expressed transcripts were identified, including many genes involved in lipid metabolism, such as L-FABP, adiponectin, PPAR-α, PPAR-β, and IGFBP1a. Evidence presented in this study indicated that lipid metabolic process in liver may be related to the difference of carcass fat content. The relevance of PPAR-α and PPAR-β as molecular markers for fat storage in liver should be worthy of further investigation. |
| format | Article |
| id | doaj-art-99979b96dc874f349697c12b079a5404 |
| institution | Kabale University |
| issn | 2314-436X 2314-4378 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Genomics |
| spelling | doaj-art-99979b96dc874f349697c12b079a54042025-02-03T05:58:45ZengWileyInternational Journal of Genomics2314-436X2314-43782016-01-01201610.1155/2016/72815857281585Transcriptome Analyses Reveal Lipid Metabolic Process in Liver Related to the Difference of Carcass Fat Content in Rainbow Trout (Oncorhynchus mykiss)Guo Hu0Wei Gu1Peng Sun2Qingli Bai3Bingqian Wang4National and Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fishery Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, ChinaNational and Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fishery Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, ChinaNational and Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fishery Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, ChinaNational and Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fishery Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, ChinaNational and Local Joint Engineering Laboratory for Freshwater Fish Breeding, Heilongjiang River Fishery Research Institute, Chinese Academy of Fishery Sciences, Harbin 150070, ChinaExcessive accumulation of carcass fat in farm animals, including fish, has a significant impact on meat quality and on the cost of feeding. Similar to farmed animals and humans, the liver can be considered one of the most important organs involved in lipid metabolism in rainbow trout (Oncorhynchus mykiss). RNA-seq based whole transcriptome sequencing was performed to liver tissue of rainbow trout with high and low carcass fat content in this study. In total 1,694 differentially expressed transcripts were identified, including many genes involved in lipid metabolism, such as L-FABP, adiponectin, PPAR-α, PPAR-β, and IGFBP1a. Evidence presented in this study indicated that lipid metabolic process in liver may be related to the difference of carcass fat content. The relevance of PPAR-α and PPAR-β as molecular markers for fat storage in liver should be worthy of further investigation.http://dx.doi.org/10.1155/2016/7281585 |
| spellingShingle | Guo Hu Wei Gu Peng Sun Qingli Bai Bingqian Wang Transcriptome Analyses Reveal Lipid Metabolic Process in Liver Related to the Difference of Carcass Fat Content in Rainbow Trout (Oncorhynchus mykiss) International Journal of Genomics |
| title | Transcriptome Analyses Reveal Lipid Metabolic Process in Liver Related to the Difference of Carcass Fat Content in Rainbow Trout (Oncorhynchus mykiss) |
| title_full | Transcriptome Analyses Reveal Lipid Metabolic Process in Liver Related to the Difference of Carcass Fat Content in Rainbow Trout (Oncorhynchus mykiss) |
| title_fullStr | Transcriptome Analyses Reveal Lipid Metabolic Process in Liver Related to the Difference of Carcass Fat Content in Rainbow Trout (Oncorhynchus mykiss) |
| title_full_unstemmed | Transcriptome Analyses Reveal Lipid Metabolic Process in Liver Related to the Difference of Carcass Fat Content in Rainbow Trout (Oncorhynchus mykiss) |
| title_short | Transcriptome Analyses Reveal Lipid Metabolic Process in Liver Related to the Difference of Carcass Fat Content in Rainbow Trout (Oncorhynchus mykiss) |
| title_sort | transcriptome analyses reveal lipid metabolic process in liver related to the difference of carcass fat content in rainbow trout oncorhynchus mykiss |
| url | http://dx.doi.org/10.1155/2016/7281585 |
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