Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics

Investigating the mechanisms of resveratrol in the treatment of gouty arthritis through the integration of network pharmacology and metabolics

ObjectiveThis study integrates network pharmacology and metabolomics techniques to explore the potential regulatory mechanisms of Res on gouty arthritis (GA).MethodsNetwork pharmacology was used to predict the mechanism of Res in regulating GA, and methods such as HE staining, ELISA, immunohistochem...

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Bibliographic Details
Main Authors: Xiaomin Xu, Donghua Yu, Yu Wang, Xin Jiang, Fang Lu, Shumin Liu
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-10-01
Series:Frontiers in Endocrinology
Subjects:
metabonomics
network pharmacology
gouty arthritis
resveratrol
NF- kappa B
MAPK
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2024.1438405/full
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