Successful Pregnancy after Simultaneous Pancreas-Kidney Transplantation

The effect of pregnancy on simultaneous pancreas-kidney transplant recipients has previously been described, but experience is limited. We describe the case of a thirty-five-year-old female who previously underwent simultaneous pancreas-kidney transplant for type 1 diabetes mellitus-complicated neph...

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Main Authors: A. Smyth, G. Gaffney, D. Hickey, D. Lappin, D. Reddan, F. Dunne
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Obstetrics and Gynecology
Online Access:http://dx.doi.org/10.1155/2011/983592
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author A. Smyth
G. Gaffney
D. Hickey
D. Lappin
D. Reddan
F. Dunne
author_facet A. Smyth
G. Gaffney
D. Hickey
D. Lappin
D. Reddan
F. Dunne
author_sort A. Smyth
collection DOAJ
description The effect of pregnancy on simultaneous pancreas-kidney transplant recipients has previously been described, but experience is limited. We describe the case of a thirty-five-year-old female who previously underwent simultaneous pancreas-kidney transplant for type 1 diabetes mellitus-complicated nephropathy. An integrated multidisciplinary team including the transplant team, nephrologist, endocrinologist, and obstetrician closely followed progress during pregnancy. Blood glucose levels and HbA1c remained within normal limits, and she did not require insulin treatment at any point. She experienced deterioration in renal indices and underwent an uncomplicated, elective Caesarean section at thirty-week gestation. She delivered a male infant of 1.18 kg, appropriate for gestational age, who had hypothermia and respiratory distress, which required intubation and ventilation and an eleven-week stay in the special care baby unit. At eighteen-month followup the infant shows normal development, and there has been no deterioration in either grafts' function.
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institution Kabale University
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series Case Reports in Obstetrics and Gynecology
spelling doaj-art-99856216fc814c239c83d1333b9fb5a42025-02-03T01:01:46ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922011-01-01201110.1155/2011/983592983592Successful Pregnancy after Simultaneous Pancreas-Kidney TransplantationA. Smyth0G. Gaffney1D. Hickey2D. Lappin3D. Reddan4F. Dunne5Department of Endocrinology, Galway University Hospitals, Galway, IrelandDepartment of Obstetrics & Gynaecology, Galway University Hospitals, Galway, IrelandDepartment of Urology & Transplantation, Beaumont Hospital, Dublin, IrelandDepartment of Nephrology, Galway University Hospitals, Galway, IrelandDepartment of Nephrology, Galway University Hospitals, Galway, IrelandDepartment of Endocrinology, Galway University Hospitals, Galway, IrelandThe effect of pregnancy on simultaneous pancreas-kidney transplant recipients has previously been described, but experience is limited. We describe the case of a thirty-five-year-old female who previously underwent simultaneous pancreas-kidney transplant for type 1 diabetes mellitus-complicated nephropathy. An integrated multidisciplinary team including the transplant team, nephrologist, endocrinologist, and obstetrician closely followed progress during pregnancy. Blood glucose levels and HbA1c remained within normal limits, and she did not require insulin treatment at any point. She experienced deterioration in renal indices and underwent an uncomplicated, elective Caesarean section at thirty-week gestation. She delivered a male infant of 1.18 kg, appropriate for gestational age, who had hypothermia and respiratory distress, which required intubation and ventilation and an eleven-week stay in the special care baby unit. At eighteen-month followup the infant shows normal development, and there has been no deterioration in either grafts' function.http://dx.doi.org/10.1155/2011/983592
spellingShingle A. Smyth
G. Gaffney
D. Hickey
D. Lappin
D. Reddan
F. Dunne
Successful Pregnancy after Simultaneous Pancreas-Kidney Transplantation
Case Reports in Obstetrics and Gynecology
title Successful Pregnancy after Simultaneous Pancreas-Kidney Transplantation
title_full Successful Pregnancy after Simultaneous Pancreas-Kidney Transplantation
title_fullStr Successful Pregnancy after Simultaneous Pancreas-Kidney Transplantation
title_full_unstemmed Successful Pregnancy after Simultaneous Pancreas-Kidney Transplantation
title_short Successful Pregnancy after Simultaneous Pancreas-Kidney Transplantation
title_sort successful pregnancy after simultaneous pancreas kidney transplantation
url http://dx.doi.org/10.1155/2011/983592
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