Staphylococcus aureus Myocarditis with Associated Left Ventricular Apical Thrombus

Staphylococcus aureus myocarditis is a rare diagnosis with a high mortality rate, usually seen in people who are immunocompromised. Here, we report a case of a 44-year-old man on methotrexate for rheumatoid arthritis who presented in septic shock and was diagnosed with staphylococcus aureus myocardi...

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Main Authors: Michael McGee, Emily Shiel, Stephen Brienesse, Stuart Murch, Robert Pickles, James Leitch
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Case Reports in Cardiology
Online Access:http://dx.doi.org/10.1155/2018/7017286
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author Michael McGee
Emily Shiel
Stephen Brienesse
Stuart Murch
Robert Pickles
James Leitch
author_facet Michael McGee
Emily Shiel
Stephen Brienesse
Stuart Murch
Robert Pickles
James Leitch
author_sort Michael McGee
collection DOAJ
description Staphylococcus aureus myocarditis is a rare diagnosis with a high mortality rate, usually seen in people who are immunocompromised. Here, we report a case of a 44-year-old man on methotrexate for rheumatoid arthritis who presented in septic shock and was diagnosed with staphylococcus aureus myocarditis. The myocarditis was associated with a left ventricular apical thrombus, with normal systolic function. The myocarditis and associated thrombus were characterised on transthoracic echocardiogram and subsequently on cardiac magnetic resonance imaging. Cardiac magnetic resonance (CMR) imaging showed oedema in the endomyocardium, consistent with acute myocarditis, associated with an apical mural thrombus. Repeat CMR 3 weeks following discharge from hospital showed marked improvement in endomyocardial oedema and complete resolution of the apical mural thrombus. He was treated with a 12-week course of antibiotics and anticoagulated with apixaban. The patient was successfully managed with intravenous antibiotics and anticoagulation with complete recovery.
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spelling doaj-art-997b65cd806e4d3e8f9c89112c9943212025-02-03T05:50:33ZengWileyCase Reports in Cardiology2090-64042090-64122018-01-01201810.1155/2018/70172867017286Staphylococcus aureus Myocarditis with Associated Left Ventricular Apical ThrombusMichael McGee0Emily Shiel1Stephen Brienesse2Stuart Murch3Robert Pickles4James Leitch5Cardiovascular Department, John Hunter Hospital, Lookout Road, New Lambton Heights, NSW 2305, AustraliaInfectious Diseases Department, John Hunter Hospital, Lookout Road, New Lambton Heights, NSW 2305, AustraliaCardiovascular Department, John Hunter Hospital, Lookout Road, New Lambton Heights, NSW 2305, AustraliaCardiovascular Department, John Hunter Hospital, Lookout Road, New Lambton Heights, NSW 2305, AustraliaInfectious Diseases Department, John Hunter Hospital, Lookout Road, New Lambton Heights, NSW 2305, AustraliaCardiovascular Department, John Hunter Hospital, Lookout Road, New Lambton Heights, NSW 2305, AustraliaStaphylococcus aureus myocarditis is a rare diagnosis with a high mortality rate, usually seen in people who are immunocompromised. Here, we report a case of a 44-year-old man on methotrexate for rheumatoid arthritis who presented in septic shock and was diagnosed with staphylococcus aureus myocarditis. The myocarditis was associated with a left ventricular apical thrombus, with normal systolic function. The myocarditis and associated thrombus were characterised on transthoracic echocardiogram and subsequently on cardiac magnetic resonance imaging. Cardiac magnetic resonance (CMR) imaging showed oedema in the endomyocardium, consistent with acute myocarditis, associated with an apical mural thrombus. Repeat CMR 3 weeks following discharge from hospital showed marked improvement in endomyocardial oedema and complete resolution of the apical mural thrombus. He was treated with a 12-week course of antibiotics and anticoagulated with apixaban. The patient was successfully managed with intravenous antibiotics and anticoagulation with complete recovery.http://dx.doi.org/10.1155/2018/7017286
spellingShingle Michael McGee
Emily Shiel
Stephen Brienesse
Stuart Murch
Robert Pickles
James Leitch
Staphylococcus aureus Myocarditis with Associated Left Ventricular Apical Thrombus
Case Reports in Cardiology
title Staphylococcus aureus Myocarditis with Associated Left Ventricular Apical Thrombus
title_full Staphylococcus aureus Myocarditis with Associated Left Ventricular Apical Thrombus
title_fullStr Staphylococcus aureus Myocarditis with Associated Left Ventricular Apical Thrombus
title_full_unstemmed Staphylococcus aureus Myocarditis with Associated Left Ventricular Apical Thrombus
title_short Staphylococcus aureus Myocarditis with Associated Left Ventricular Apical Thrombus
title_sort staphylococcus aureus myocarditis with associated left ventricular apical thrombus
url http://dx.doi.org/10.1155/2018/7017286
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AT stuartmurch staphylococcusaureusmyocarditiswithassociatedleftventricularapicalthrombus
AT robertpickles staphylococcusaureusmyocarditiswithassociatedleftventricularapicalthrombus
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