Optogenetic Inhibition of Striatal Neuronal Activity Improves the Survival of Transplanted Neural Stem Cells and Neurological Outcomes after Ischemic Stroke in Mice

Neural stem cell (NSC) transplantation is a promising treatment to improve the recovery after brain ischemia. However, how the survival, proliferation, migration, and differentiation of implanted NSC are influenced by endogenous neuronal activity remains unclear. In this work, we used optogenetic te...

Full description

Saved in:
Bibliographic Details
Main Authors: Yifan Lu, Lu Jiang, Wanlu Li, Meijie Qu, Yaying Song, Xiaosong He, Zhijun Zhang, Guo-Yuan Yang, Yongting Wang
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2017/4364302
Tags: Add Tag
No Tags, Be the first to tag this record!