Speculation of the Time-Dependent Change of FIB4 Index in Patients with Nonalcoholic Fatty Liver Disease: A Retrospective Study

Aim. To speculate on the time-dependent change of FIB4 index in patients with nonalcoholic fatty liver disease (NAFLD) and its increase-decrease rate per year, simply and accurately. Methods. In all 23 patients with NAFLD with the value of FIB4 index over 1.30 at the peak, the period from the first...

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Main Authors: Hiroshi Miyata, Satoru Miyata
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2018/5323061
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author Hiroshi Miyata
Satoru Miyata
author_facet Hiroshi Miyata
Satoru Miyata
author_sort Hiroshi Miyata
collection DOAJ
description Aim. To speculate on the time-dependent change of FIB4 index in patients with nonalcoholic fatty liver disease (NAFLD) and its increase-decrease rate per year, simply and accurately. Methods. In all 23 patients with NAFLD with the value of FIB4 index over 1.30 at the peak, the period from the first to each examination date was calculated and this period (years) was regarded as x. Next, the mean value of FIB4 index during the past year to each examination date was regarded as y. In every y, the minimum and the maximum y value were found out. Between x corresponding to this minimum y and x corresponding to this maximum y, the correlation between x and y was analyzed as the main subject. Then, the slope of each correlation was investigated, because it should indicate increase-decrease rate per year. Results. In all 23 patients, the correlations as the main subject were recognized and the mean absolute value of correlation coefficient (r) was 0.91±0.08. As for the slope, the mean absolute value was 0.1371±0.1147 (/year). Conclusion. Simply and accurately, the time-dependent change of FIB4 index and its increase-decrease rate per year could be approximately speculated.
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spelling doaj-art-9969983fd07948d0b6a40b1fd0e060942025-02-03T01:00:48ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972018-01-01201810.1155/2018/53230615323061Speculation of the Time-Dependent Change of FIB4 Index in Patients with Nonalcoholic Fatty Liver Disease: A Retrospective StudyHiroshi Miyata0Satoru Miyata1Sugimoto Clinic, 3-2-27 Yamanouchi, Sumiyoshi-ku, Osaka city, Osaka-fu 558-0023, JapanSugimoto Clinic, 3-2-27 Yamanouchi, Sumiyoshi-ku, Osaka city, Osaka-fu 558-0023, JapanAim. To speculate on the time-dependent change of FIB4 index in patients with nonalcoholic fatty liver disease (NAFLD) and its increase-decrease rate per year, simply and accurately. Methods. In all 23 patients with NAFLD with the value of FIB4 index over 1.30 at the peak, the period from the first to each examination date was calculated and this period (years) was regarded as x. Next, the mean value of FIB4 index during the past year to each examination date was regarded as y. In every y, the minimum and the maximum y value were found out. Between x corresponding to this minimum y and x corresponding to this maximum y, the correlation between x and y was analyzed as the main subject. Then, the slope of each correlation was investigated, because it should indicate increase-decrease rate per year. Results. In all 23 patients, the correlations as the main subject were recognized and the mean absolute value of correlation coefficient (r) was 0.91±0.08. As for the slope, the mean absolute value was 0.1371±0.1147 (/year). Conclusion. Simply and accurately, the time-dependent change of FIB4 index and its increase-decrease rate per year could be approximately speculated.http://dx.doi.org/10.1155/2018/5323061
spellingShingle Hiroshi Miyata
Satoru Miyata
Speculation of the Time-Dependent Change of FIB4 Index in Patients with Nonalcoholic Fatty Liver Disease: A Retrospective Study
Canadian Journal of Gastroenterology and Hepatology
title Speculation of the Time-Dependent Change of FIB4 Index in Patients with Nonalcoholic Fatty Liver Disease: A Retrospective Study
title_full Speculation of the Time-Dependent Change of FIB4 Index in Patients with Nonalcoholic Fatty Liver Disease: A Retrospective Study
title_fullStr Speculation of the Time-Dependent Change of FIB4 Index in Patients with Nonalcoholic Fatty Liver Disease: A Retrospective Study
title_full_unstemmed Speculation of the Time-Dependent Change of FIB4 Index in Patients with Nonalcoholic Fatty Liver Disease: A Retrospective Study
title_short Speculation of the Time-Dependent Change of FIB4 Index in Patients with Nonalcoholic Fatty Liver Disease: A Retrospective Study
title_sort speculation of the time dependent change of fib4 index in patients with nonalcoholic fatty liver disease a retrospective study
url http://dx.doi.org/10.1155/2018/5323061
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