Discovery of Synergistic Broadly Neutralizing Antibodies Targeting Non-Dominant Epitopes on SARS-CoV-2 RBD and NTD

Discovery of Synergistic Broadly Neutralizing Antibodies Targeting Non-Dominant Epitopes on SARS-CoV-2 RBD and NTD

<b>Background/Objectives</b>: Identification and characterization of broadly neutralizing monoclonal antibodies from individuals exposed to SARS-CoV-2, either by infection or vaccination, can inform the development of next-generation vaccines and antibody therapeutics with pan-SARS-CoV-2...

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Bibliographic Details
Main Authors: Hualong Feng, Zuowei Wang, Ling Li, Yunjian Li, Maosheng Lu, Xixian Chen, Lin Hu, Yi Sun, Ruiping Du, Rongrong Qin, Xuanyi Chen, Liwei Jiang, Teng Zuo
Format: Article
Language:English
Published: MDPI AG 2025-05-01
Series:Vaccines
Subjects:
SARS-CoV-2
broadly neutralizing monoclonal antibodies
epitope mapping
RBD-8
NTD Site iv
antibody cocktail
Online Access:https://www.mdpi.com/2076-393X/13/6/592
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