FBXW7 metabolic reprogramming inhibits the development of colon cancer by down-regulating the activity of arginine/mToR pathways.
FBXW7 is a tumor suppressor gene that regulates metabolism and is associated with the onset and progression of colorectal cancer (CRC)), however, the precise mechanism whereby FBXW7 participates in the metabolic reprogramming of CRC remains unclear. Here, the research aims to reveal the association...
Saved in:
Main Authors: | Qing Li, Yan Li, Tong Zhou, Yong Zhang, Huiyu Li, Fajia Yuan, Yanghui Bi |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2025-01-01
|
Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0317294 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A
by: Xing Wang, et al.
Published: (2022-01-01) -
PRMT7: A Pivotal Arginine Methyltransferase in Stem Cells and Development
by: Bingyuan Wang, et al.
Published: (2021-01-01) -
ZNF169 promotes thyroid cancer progression via upregulating FBXW10
by: Wen Luo, et al.
Published: (2025-01-01) -
GC-derived exosomal circMAN1A2 promotes cancer progression and suppresses T-cell antitumour immunity by inhibiting FBXW11-mediated SFPQ degradation
by: Yikai Shen, et al.
Published: (2025-01-01) -
mTOR Inhibition: From Aging to Autism and Beyond
by: Matt Kaeberlein
Published: (2013-01-01)