Clinically probable RBD is an early predictor of malignant non-motor Parkinson’s disease phenotypes

Clinically probable RBD is an early predictor of malignant non-motor Parkinson’s disease phenotypes

Abstract Non-motor symptoms (NMS) in Parkinson’s disease (PD) significantly impact quality of life, especially in later stages. REM sleep behavior disorder (RBD) affects approximately 42% of all PD patients and frequently precedes motor PD symptoms. RBD is linked to increased rates of depression and...

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Main Authors: Alfonso Enrique Martinez-Nunez, Hunter Hutchinson, Patricia Coutinho, Filipe Pereira Sarmento, Venkat Srikar Lavu, Qingqi Yuan, Jagan Mohan Reddy Dwarampudi, Aysegul Gunduz, Gregory M. Pontone, Michael S. Okun, Joshua K. Wong
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-00874-8
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