Psoriasis and Cardiovascular Risk: Assessment by CUORE Project Risk Score in Italian Patients
Background. Psoriasis is a common inflammatory and immune-mediated skin disease. There is growing controversy as to whether cardiovascular risk is elevated in psoriasis. A number of studies suggest a high prevalence of cardiovascular risk factors as well as cardiovascular diseases in psoriasis patie...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
|
| Series: | Dermatology Research and Practice |
| Online Access: | http://dx.doi.org/10.1155/2013/389031 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832554510352908288 |
|---|---|
| author | Spyridoula Doukaki Valentina Caputo Maria Rita Bongiorno |
| author_facet | Spyridoula Doukaki Valentina Caputo Maria Rita Bongiorno |
| author_sort | Spyridoula Doukaki |
| collection | DOAJ |
| description | Background. Psoriasis is a common inflammatory and immune-mediated skin disease. There is growing controversy as to whether cardiovascular risk is elevated in psoriasis. A number of studies suggest a high prevalence of cardiovascular risk factors as well as cardiovascular diseases in psoriasis patients.
Objective. The objective of this study was to estimate cardiovascular risk score in psoriasis patients and the relation between cardiovascular risk and psoriasis features. Cardiovascular risk was assessed by CUORE project risk score built within the longitudinal study of the Italian CUORE project and suited to populations with a low rate of coronary heart disease. Results. A case-control study in 210 psoriasis outpatients and 111 controls with skin diseases other than psoriasis was performed. CUORE project risk score was higher in patients than controls ( versus , ). Compared to controls, psoriasis patients have higher risk of developing major cardiovascular events. Cardiovascular risk was not related to psoriasis characteristics. Conclusion. Increased focus on identifying cardiovascular risk factors and initiation of preventive lifestyle changes or therapeutic interventions in patients with psoriasis is warranted. |
| format | Article |
| id | doaj-art-9929bed7c469449a8c96687875532279 |
| institution | Kabale University |
| issn | 1687-6105 1687-6113 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Dermatology Research and Practice |
| spelling | doaj-art-9929bed7c469449a8c966878755322792025-02-03T05:51:18ZengWileyDermatology Research and Practice1687-61051687-61132013-01-01201310.1155/2013/389031389031Psoriasis and Cardiovascular Risk: Assessment by CUORE Project Risk Score in Italian PatientsSpyridoula Doukaki0Valentina Caputo1Maria Rita Bongiorno2Department of Dermatology, University of Palermo, Via del Vespro 131, 90123 Palermo, ItalyDepartment of Dermatology, University of Palermo, Via del Vespro 131, 90123 Palermo, ItalyDepartment of Dermatology, University of Palermo, Via del Vespro 131, 90123 Palermo, ItalyBackground. Psoriasis is a common inflammatory and immune-mediated skin disease. There is growing controversy as to whether cardiovascular risk is elevated in psoriasis. A number of studies suggest a high prevalence of cardiovascular risk factors as well as cardiovascular diseases in psoriasis patients. Objective. The objective of this study was to estimate cardiovascular risk score in psoriasis patients and the relation between cardiovascular risk and psoriasis features. Cardiovascular risk was assessed by CUORE project risk score built within the longitudinal study of the Italian CUORE project and suited to populations with a low rate of coronary heart disease. Results. A case-control study in 210 psoriasis outpatients and 111 controls with skin diseases other than psoriasis was performed. CUORE project risk score was higher in patients than controls ( versus , ). Compared to controls, psoriasis patients have higher risk of developing major cardiovascular events. Cardiovascular risk was not related to psoriasis characteristics. Conclusion. Increased focus on identifying cardiovascular risk factors and initiation of preventive lifestyle changes or therapeutic interventions in patients with psoriasis is warranted.http://dx.doi.org/10.1155/2013/389031 |
| spellingShingle | Spyridoula Doukaki Valentina Caputo Maria Rita Bongiorno Psoriasis and Cardiovascular Risk: Assessment by CUORE Project Risk Score in Italian Patients Dermatology Research and Practice |
| title | Psoriasis and Cardiovascular Risk: Assessment by CUORE Project Risk Score in Italian Patients |
| title_full | Psoriasis and Cardiovascular Risk: Assessment by CUORE Project Risk Score in Italian Patients |
| title_fullStr | Psoriasis and Cardiovascular Risk: Assessment by CUORE Project Risk Score in Italian Patients |
| title_full_unstemmed | Psoriasis and Cardiovascular Risk: Assessment by CUORE Project Risk Score in Italian Patients |
| title_short | Psoriasis and Cardiovascular Risk: Assessment by CUORE Project Risk Score in Italian Patients |
| title_sort | psoriasis and cardiovascular risk assessment by cuore project risk score in italian patients |
| url | http://dx.doi.org/10.1155/2013/389031 |
| work_keys_str_mv | AT spyridouladoukaki psoriasisandcardiovascularriskassessmentbycuoreprojectriskscoreinitalianpatients AT valentinacaputo psoriasisandcardiovascularriskassessmentbycuoreprojectriskscoreinitalianpatients AT mariaritabongiorno psoriasisandcardiovascularriskassessmentbycuoreprojectriskscoreinitalianpatients |