Deficiency of Interleukin-1 Receptor Antagonist: A Case with Late Onset Severe Inflammatory Arthritis, Nail Psoriasis with Onychomycosis and Well Responsive to Adalimumab Therapy

DIRA (deficiency of the IL-1Ra) is a rare condition that usually presents in the neonatal period. Patients with DIRA present with systemic inflammation, respiratory distress, joint swelling, pustular rash, multifocal osteomyelitis, and periostitis. Previously, we reported a patient with a novel muta...

Full description

Saved in:
Bibliographic Details
Main Authors: Necil Kutukculer, Anne Puel, Sanem Eren Akarcan, Kunihiko Moriya, Neslihan Edeer Karaca, Melanie Migaud, Jean-Laurent Casanova, Guzide Aksu
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Immunology
Online Access:http://dx.doi.org/10.1155/2019/1902817
Tags: Add Tag
No Tags, Be the first to tag this record!