Componential Profile and Amylase Inhibiting Activity of Phenolic Compounds from Calendula officinalis L. Leaves
An ethanolic extract and its ethyl acetate-soluble fraction from leaves of Calendula officinalis L. (Asteraceae) were found to show an inhibitory effect on amylase. From the crude extract fractions, one new phenolic acid glucoside, 6′-O-vanilloyl-β-D-glucopyranose, was isolated, together with twenty...
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Wiley
2014-01-01
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| Series: | The Scientific World Journal |
| Online Access: | http://dx.doi.org/10.1155/2014/654193 |
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| author | Daniil N. Olennikov Nina I. Kashchenko |
| author_facet | Daniil N. Olennikov Nina I. Kashchenko |
| author_sort | Daniil N. Olennikov |
| collection | DOAJ |
| description | An ethanolic extract and its ethyl acetate-soluble fraction from leaves of Calendula officinalis L. (Asteraceae) were found to show an inhibitory effect on amylase. From the crude extract fractions, one new phenolic acid glucoside, 6′-O-vanilloyl-β-D-glucopyranose, was isolated, together with twenty-four known compounds including five phenolic acid glucosides, five phenylpropanoids, five coumarins, and nine flavonoids. Their structures were elucidated based on chemical and spectral data. The main components, isoquercitrin, isorhamnetin-3-O-β-D-glucopyranoside, 3,5-di-O-caffeoylquinic acid, and quercetin-3-O-(6′′-acetyl)-β-D-glucopyranoside, exhibited potent inhibitory effects on amylase. |
| format | Article |
| id | doaj-art-991b08d5ee9240fd9142def0a927368a |
| institution | Kabale University |
| issn | 2356-6140 1537-744X |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | The Scientific World Journal |
| spelling | doaj-art-991b08d5ee9240fd9142def0a927368a2025-02-03T06:05:58ZengWileyThe Scientific World Journal2356-61401537-744X2014-01-01201410.1155/2014/654193654193Componential Profile and Amylase Inhibiting Activity of Phenolic Compounds from Calendula officinalis L. LeavesDaniil N. Olennikov0Nina I. Kashchenko1Laboratory of Medical and Biological Research, Institute of General and Experimental Biology, Siberian Division, Russian Academy of Science, Sakh’yanovoy Street, 6, Ulan-Ude 670047, RussiaLaboratory of Medical and Biological Research, Institute of General and Experimental Biology, Siberian Division, Russian Academy of Science, Sakh’yanovoy Street, 6, Ulan-Ude 670047, RussiaAn ethanolic extract and its ethyl acetate-soluble fraction from leaves of Calendula officinalis L. (Asteraceae) were found to show an inhibitory effect on amylase. From the crude extract fractions, one new phenolic acid glucoside, 6′-O-vanilloyl-β-D-glucopyranose, was isolated, together with twenty-four known compounds including five phenolic acid glucosides, five phenylpropanoids, five coumarins, and nine flavonoids. Their structures were elucidated based on chemical and spectral data. The main components, isoquercitrin, isorhamnetin-3-O-β-D-glucopyranoside, 3,5-di-O-caffeoylquinic acid, and quercetin-3-O-(6′′-acetyl)-β-D-glucopyranoside, exhibited potent inhibitory effects on amylase.http://dx.doi.org/10.1155/2014/654193 |
| spellingShingle | Daniil N. Olennikov Nina I. Kashchenko Componential Profile and Amylase Inhibiting Activity of Phenolic Compounds from Calendula officinalis L. Leaves The Scientific World Journal |
| title | Componential Profile and Amylase Inhibiting Activity of Phenolic Compounds from Calendula officinalis L. Leaves |
| title_full | Componential Profile and Amylase Inhibiting Activity of Phenolic Compounds from Calendula officinalis L. Leaves |
| title_fullStr | Componential Profile and Amylase Inhibiting Activity of Phenolic Compounds from Calendula officinalis L. Leaves |
| title_full_unstemmed | Componential Profile and Amylase Inhibiting Activity of Phenolic Compounds from Calendula officinalis L. Leaves |
| title_short | Componential Profile and Amylase Inhibiting Activity of Phenolic Compounds from Calendula officinalis L. Leaves |
| title_sort | componential profile and amylase inhibiting activity of phenolic compounds from calendula officinalis l leaves |
| url | http://dx.doi.org/10.1155/2014/654193 |
| work_keys_str_mv | AT daniilnolennikov componentialprofileandamylaseinhibitingactivityofphenoliccompoundsfromcalendulaofficinalislleaves AT ninaikashchenko componentialprofileandamylaseinhibitingactivityofphenoliccompoundsfromcalendulaofficinalislleaves |