Calcific Uremic Arteriolopathy in Peritoneal Dialysis Populations
Calciphylaxis or calcific uremic arteriolopathy is an infrequent complication of end stage kidney disease. It is characterized by arteriolar medial calcification, thrombotic cutaneous ischemia, tissue necrosis often leading to ulceration, secondary infection and increased mortality rates. Current, m...
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Nephrology |
| Online Access: | http://dx.doi.org/10.4061/2011/982854 |
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| author | Nicholas New Janaki Mohandas George T. John Sharad Ratanjee Helen Healy Leo Francis Dwarakanathan Ranganathan |
| author_facet | Nicholas New Janaki Mohandas George T. John Sharad Ratanjee Helen Healy Leo Francis Dwarakanathan Ranganathan |
| author_sort | Nicholas New |
| collection | DOAJ |
| description | Calciphylaxis or calcific uremic arteriolopathy is an infrequent complication of end stage kidney disease. It is characterized by arteriolar medial calcification, thrombotic cutaneous ischemia, tissue necrosis often leading to ulceration, secondary infection and increased mortality rates. Current, multimodality treatment involves local wound care, well-controlled calcium, phosphate and parathyroid hormone levels and combination therapy with sodium thiosulfate and hyperbaric oxygen therapy. This combination therapy may be changing the historically poor prognosis of calcific uremic arteriolopathy reported in the literature. Peritoneal dialysis is considered a risk factor based on limited publications, however this remains to be proven. Clinical presentation, diagnosis, pathogenesis and treatment of calcific uremic arteriolopathy in these patients are no different from other patients manifesting with this condition. |
| format | Article |
| id | doaj-art-98f7d76831fa40548da3f3b4023f6a88 |
| institution | Kabale University |
| issn | 2090-214X 2090-2158 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Nephrology |
| spelling | doaj-art-98f7d76831fa40548da3f3b4023f6a882025-02-03T05:44:47ZengWileyInternational Journal of Nephrology2090-214X2090-21582011-01-01201110.4061/2011/982854982854Calcific Uremic Arteriolopathy in Peritoneal Dialysis PopulationsNicholas New0Janaki Mohandas1George T. John2Sharad Ratanjee3Helen Healy4Leo Francis5Dwarakanathan Ranganathan6Department of Nephrology, Royal Brisbane and Women’s Hospital, Queensland Health, Butterfield Street, Herston, QLD 4029, AustraliaDepartment of Nephrology, Royal Brisbane and Women’s Hospital, Queensland Health, Butterfield Street, Herston, QLD 4029, AustraliaDepartment of Nephrology, Royal Brisbane and Women’s Hospital, Queensland Health, Butterfield Street, Herston, QLD 4029, AustraliaDepartment of Nephrology, Royal Brisbane and Women’s Hospital, Queensland Health, Butterfield Street, Herston, QLD 4029, AustraliaDepartment of Nephrology, Royal Brisbane and Women’s Hospital, Queensland Health, Butterfield Street, Herston, QLD 4029, AustraliaDepartment of Anatomical Pathology, Royal Brisbane and Women’s Hospital, Queensland Health, Butterfield Street, Herston, QLD 4029, AustraliaDepartment of Nephrology, Royal Brisbane and Women’s Hospital, Queensland Health, Butterfield Street, Herston, QLD 4029, AustraliaCalciphylaxis or calcific uremic arteriolopathy is an infrequent complication of end stage kidney disease. It is characterized by arteriolar medial calcification, thrombotic cutaneous ischemia, tissue necrosis often leading to ulceration, secondary infection and increased mortality rates. Current, multimodality treatment involves local wound care, well-controlled calcium, phosphate and parathyroid hormone levels and combination therapy with sodium thiosulfate and hyperbaric oxygen therapy. This combination therapy may be changing the historically poor prognosis of calcific uremic arteriolopathy reported in the literature. Peritoneal dialysis is considered a risk factor based on limited publications, however this remains to be proven. Clinical presentation, diagnosis, pathogenesis and treatment of calcific uremic arteriolopathy in these patients are no different from other patients manifesting with this condition.http://dx.doi.org/10.4061/2011/982854 |
| spellingShingle | Nicholas New Janaki Mohandas George T. John Sharad Ratanjee Helen Healy Leo Francis Dwarakanathan Ranganathan Calcific Uremic Arteriolopathy in Peritoneal Dialysis Populations International Journal of Nephrology |
| title | Calcific Uremic Arteriolopathy in Peritoneal Dialysis Populations |
| title_full | Calcific Uremic Arteriolopathy in Peritoneal Dialysis Populations |
| title_fullStr | Calcific Uremic Arteriolopathy in Peritoneal Dialysis Populations |
| title_full_unstemmed | Calcific Uremic Arteriolopathy in Peritoneal Dialysis Populations |
| title_short | Calcific Uremic Arteriolopathy in Peritoneal Dialysis Populations |
| title_sort | calcific uremic arteriolopathy in peritoneal dialysis populations |
| url | http://dx.doi.org/10.4061/2011/982854 |
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