Incidental imaging detection of Kartagener syndrome in a female: A case report
Kartagener syndrome is a rare ciliopathic genetic disorder characterized by a triad of chronic sinusitis, situs inversus, and bronchiectasis. The underlying pathophysiology involves reduced ciliary motility due to defects in ciliary structure and function within the respiratory tract and fallopian t...
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| Format: | Article |
| Language: | English |
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Elsevier
2025-03-01
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| Series: | Radiology Case Reports |
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S1930043324013542 |
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| author | Natasha Dhakal, MBBS Prajwal Dahal, MD |
| author_facet | Natasha Dhakal, MBBS Prajwal Dahal, MD |
| author_sort | Natasha Dhakal, MBBS |
| collection | DOAJ |
| description | Kartagener syndrome is a rare ciliopathic genetic disorder characterized by a triad of chronic sinusitis, situs inversus, and bronchiectasis. The underlying pathophysiology involves reduced ciliary motility due to defects in ciliary structure and function within the respiratory tract and fallopian tubes. Diagnosis is typically confirmed through imaging studies such as X-rays, CT scans, and echocardiograms, which reveal the abnormal orientation of the heart and other organs. Treatment depends on the presence of associated conditions, such as congenital heart defects, respiratory infections and appropriate interventions with regular follow-up can help prevent complications. In this case, we present a 32-year-old female with a history of secondary infertility who presented with recurrent cough and fever. A thorough clinical examination was conducted, followed by radiological investigations that revealed chronic sinusitis, bronchiectasis, dextrocardia, and situs inversus totalis. She was subsequently treated with oral antibiotics, mucolytics, and initiated on chest physiotherapy. This case highlights the importance of considering Kartagener syndrome in patients presenting with recurrent respiratory infections and fertility issues. |
| format | Article |
| id | doaj-art-98e71276f5514138ae04b43497365569 |
| institution | Kabale University |
| issn | 1930-0433 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Radiology Case Reports |
| spelling | doaj-art-98e71276f5514138ae04b434973655692025-01-18T05:04:02ZengElsevierRadiology Case Reports1930-04332025-03-0120315171521Incidental imaging detection of Kartagener syndrome in a female: A case reportNatasha Dhakal, MBBS0Prajwal Dahal, MD1Manmohan Cardiothoracic Vascular and Transplant Center, Kathmandu, NepalDepartment of Radiology and Imaging, Grande International Hospital, Kathmandu, Nepal; Corresponding author.Kartagener syndrome is a rare ciliopathic genetic disorder characterized by a triad of chronic sinusitis, situs inversus, and bronchiectasis. The underlying pathophysiology involves reduced ciliary motility due to defects in ciliary structure and function within the respiratory tract and fallopian tubes. Diagnosis is typically confirmed through imaging studies such as X-rays, CT scans, and echocardiograms, which reveal the abnormal orientation of the heart and other organs. Treatment depends on the presence of associated conditions, such as congenital heart defects, respiratory infections and appropriate interventions with regular follow-up can help prevent complications. In this case, we present a 32-year-old female with a history of secondary infertility who presented with recurrent cough and fever. A thorough clinical examination was conducted, followed by radiological investigations that revealed chronic sinusitis, bronchiectasis, dextrocardia, and situs inversus totalis. She was subsequently treated with oral antibiotics, mucolytics, and initiated on chest physiotherapy. This case highlights the importance of considering Kartagener syndrome in patients presenting with recurrent respiratory infections and fertility issues.http://www.sciencedirect.com/science/article/pii/S1930043324013542Kartagener syndromeSitus inversus totalisBronchiectasisInfertilityDextrocardia |
| spellingShingle | Natasha Dhakal, MBBS Prajwal Dahal, MD Incidental imaging detection of Kartagener syndrome in a female: A case report Radiology Case Reports Kartagener syndrome Situs inversus totalis Bronchiectasis Infertility Dextrocardia |
| title | Incidental imaging detection of Kartagener syndrome in a female: A case report |
| title_full | Incidental imaging detection of Kartagener syndrome in a female: A case report |
| title_fullStr | Incidental imaging detection of Kartagener syndrome in a female: A case report |
| title_full_unstemmed | Incidental imaging detection of Kartagener syndrome in a female: A case report |
| title_short | Incidental imaging detection of Kartagener syndrome in a female: A case report |
| title_sort | incidental imaging detection of kartagener syndrome in a female a case report |
| topic | Kartagener syndrome Situs inversus totalis Bronchiectasis Infertility Dextrocardia |
| url | http://www.sciencedirect.com/science/article/pii/S1930043324013542 |
| work_keys_str_mv | AT natashadhakalmbbs incidentalimagingdetectionofkartagenersyndromeinafemaleacasereport AT prajwaldahalmd incidentalimagingdetectionofkartagenersyndromeinafemaleacasereport |