Metabolic reprogramming signature predicts prognosis and immune landscape in small cell lung cancer: MOCS2 validation and implications for personalized therapy

Metabolic reprogramming signature predicts prognosis and immune landscape in small cell lung cancer: MOCS2 validation and implications for personalized therapy

IntroductionSmall cell lung cancer (SCLC) remains a leading cause of cancer mortality worldwide, characterized by rapid progression and poor clinical outcomes, and the function of metabolic reprogramming remains unclear in SCLC.MethodsWe performed multi-omics analysis using public SCLC datasets, ana...

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Bibliographic Details
Main Authors: Junyan Wang, Panpan Sun, Fan Zhang, Yu Xu, Shenghu Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Molecular Biosciences
Subjects:
metabolic reprogramming
small cell lung cancer
prognosis
immune microenvironment
drug sensitivity
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2025.1592888/full
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