Depression and Anxiety among Patients with Epilepsy and Multiple Sclerosis: UAE Comparative Study

Depression and anxiety are highly prevalent in patients with epilepsy (PWE), with prevalence rates ranging from 20% to 55%. The cause of this increased rate is multifactorial. Depression and epilepsy are thought to share the same pathogenic mechanism. Anxiety, on the other hand, seems to have a prev...

Full description

Saved in:
Bibliographic Details
Main Authors: Taoufik Alsaadi, Khadija El Hammasi, Tarek M. Shahrour, Mustafa Shakra, Lamya Turkawi, Wassim Nasreddine, Mufeed Raoof
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Behavioural Neurology
Online Access:http://dx.doi.org/10.1155/2015/196373
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832568513791787008
author Taoufik Alsaadi
Khadija El Hammasi
Tarek M. Shahrour
Mustafa Shakra
Lamya Turkawi
Wassim Nasreddine
Mufeed Raoof
author_facet Taoufik Alsaadi
Khadija El Hammasi
Tarek M. Shahrour
Mustafa Shakra
Lamya Turkawi
Wassim Nasreddine
Mufeed Raoof
author_sort Taoufik Alsaadi
collection DOAJ
description Depression and anxiety are highly prevalent in patients with epilepsy (PWE), with prevalence rates ranging from 20% to 55%. The cause of this increased rate is multifactorial. Depression and epilepsy are thought to share the same pathogenic mechanism. Anxiety, on the other hand, seems to have a prevalence rate among PWE comparable to, or even higher than, those reported for depression, and it is closely linked to epilepsy. To test this hypothesis, we screened for depression and anxiety 186 and 160 patients attending the epilepsy and MS clinics, respectively, using standardized screening tools to determine the rates of both depression and anxiety, comparing these rates to 186 age, sex matched controls. Among the three groups, only patients with epilepsy were at increased risk of having depression (OR = 1.9), whereas anxiety was not. This finding could point to the shared pathogenic mechanisms hypothesis between depression and epilepsy.
format Article
id doaj-art-98dcc9e842a74858a7c3c94d61bba159
institution Kabale University
issn 0953-4180
1875-8584
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series Behavioural Neurology
spelling doaj-art-98dcc9e842a74858a7c3c94d61bba1592025-02-03T00:58:54ZengWileyBehavioural Neurology0953-41801875-85842015-01-01201510.1155/2015/196373196373Depression and Anxiety among Patients with Epilepsy and Multiple Sclerosis: UAE Comparative StudyTaoufik Alsaadi0Khadija El Hammasi1Tarek M. Shahrour2Mustafa Shakra3Lamya Turkawi4Wassim Nasreddine5Mufeed Raoof6Department of Neurology, Sheikh Khalifa Medical City (SKMC), Abu Dhabi 51900, UAEDepartment of Psychiatry, Sheikh Khalifa Medical City (SKMC), Abu Dhabi 51900, UAEDepartment of Psychiatry, Sheikh Khalifa Medical City (SKMC), Abu Dhabi 51900, UAEDepartment of Neurology, Sheikh Khalifa Medical City (SKMC), Abu Dhabi 51900, UAEDepartment of Neurology, Sheikh Khalifa Medical City (SKMC), Abu Dhabi 51900, UAEDepartment of Neurology, American University of Beirut Medical Center, Beirut 1107, LebanonDepartment of Psychiatry, Sheikh Khalifa Medical City (SKMC), Abu Dhabi 51900, UAEDepression and anxiety are highly prevalent in patients with epilepsy (PWE), with prevalence rates ranging from 20% to 55%. The cause of this increased rate is multifactorial. Depression and epilepsy are thought to share the same pathogenic mechanism. Anxiety, on the other hand, seems to have a prevalence rate among PWE comparable to, or even higher than, those reported for depression, and it is closely linked to epilepsy. To test this hypothesis, we screened for depression and anxiety 186 and 160 patients attending the epilepsy and MS clinics, respectively, using standardized screening tools to determine the rates of both depression and anxiety, comparing these rates to 186 age, sex matched controls. Among the three groups, only patients with epilepsy were at increased risk of having depression (OR = 1.9), whereas anxiety was not. This finding could point to the shared pathogenic mechanisms hypothesis between depression and epilepsy.http://dx.doi.org/10.1155/2015/196373
spellingShingle Taoufik Alsaadi
Khadija El Hammasi
Tarek M. Shahrour
Mustafa Shakra
Lamya Turkawi
Wassim Nasreddine
Mufeed Raoof
Depression and Anxiety among Patients with Epilepsy and Multiple Sclerosis: UAE Comparative Study
Behavioural Neurology
title Depression and Anxiety among Patients with Epilepsy and Multiple Sclerosis: UAE Comparative Study
title_full Depression and Anxiety among Patients with Epilepsy and Multiple Sclerosis: UAE Comparative Study
title_fullStr Depression and Anxiety among Patients with Epilepsy and Multiple Sclerosis: UAE Comparative Study
title_full_unstemmed Depression and Anxiety among Patients with Epilepsy and Multiple Sclerosis: UAE Comparative Study
title_short Depression and Anxiety among Patients with Epilepsy and Multiple Sclerosis: UAE Comparative Study
title_sort depression and anxiety among patients with epilepsy and multiple sclerosis uae comparative study
url http://dx.doi.org/10.1155/2015/196373
work_keys_str_mv AT taoufikalsaadi depressionandanxietyamongpatientswithepilepsyandmultiplesclerosisuaecomparativestudy
AT khadijaelhammasi depressionandanxietyamongpatientswithepilepsyandmultiplesclerosisuaecomparativestudy
AT tarekmshahrour depressionandanxietyamongpatientswithepilepsyandmultiplesclerosisuaecomparativestudy
AT mustafashakra depressionandanxietyamongpatientswithepilepsyandmultiplesclerosisuaecomparativestudy
AT lamyaturkawi depressionandanxietyamongpatientswithepilepsyandmultiplesclerosisuaecomparativestudy
AT wassimnasreddine depressionandanxietyamongpatientswithepilepsyandmultiplesclerosisuaecomparativestudy
AT mufeedraoof depressionandanxietyamongpatientswithepilepsyandmultiplesclerosisuaecomparativestudy