Topographical mapping of metabolic abnormalities in multiple sclerosis using rapid echo-less 3D-MR spectroscopic imaging at 7T

Topographical mapping of metabolic abnormalities in multiple sclerosis using rapid echo-less 3D-MR spectroscopic imaging at 7T

Objectives: To assess topographical patterns of metabolic abnormalities in the cerebrum of multiple sclerosis (MS) patients and their relationship to clinical disability using rapid echo-less 3D-MR spectroscopic imaging (MRSI) at 7T. Materials and Methods: This study included 26 MS patients (13 wome...

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Bibliographic Details
Main Authors: Eva Niess, Assunta Dal-Bianco, Bernhard Strasser, Fabian Niess, Lukas Hingerl, Beata Bachrata, Stanislav Motyka, Paulus Rommer, Siegfried Trattnig, Wolfgang Bogner
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:NeuroImage
Subjects:
MRSI
Myo-inositol
N-acetylaspartate
Gliosis
Neuronal damage
Normal-appearing white matter
Online Access:http://www.sciencedirect.com/science/article/pii/S105381192500045X
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