The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches
Interplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. In the rapidly evolving field of immunooncology, understanding the tumor-specific immune response enhances understanding of cancer resistance. This review highlights the...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2016-01-01
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| Series: | Journal of Immunology Research |
| Online Access: | http://dx.doi.org/10.1155/2016/4273943 |
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| _version_ | 1832568232388591616 |
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| author | Pankita H. Pandya Mary E. Murray Karen E. Pollok Jamie L. Renbarger |
| author_facet | Pankita H. Pandya Mary E. Murray Karen E. Pollok Jamie L. Renbarger |
| author_sort | Pankita H. Pandya |
| collection | DOAJ |
| description | Interplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. In the rapidly evolving field of immunooncology, understanding the tumor-specific immune response enhances understanding of cancer resistance. This review highlights the fundamentals of incorporating precision medicine to discover new immune biomarkers and predictive signatures. Using a personalized approach may have a significant, positive impact on the use of oncolytics to better guide safer and more effective therapies. |
| format | Article |
| id | doaj-art-98ca9bfca5fa459293dd32f7ba0b53e1 |
| institution | Kabale University |
| issn | 2314-8861 2314-7156 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Immunology Research |
| spelling | doaj-art-98ca9bfca5fa459293dd32f7ba0b53e12025-02-03T00:59:31ZengWileyJournal of Immunology Research2314-88612314-71562016-01-01201610.1155/2016/42739434273943The Immune System in Cancer Pathogenesis: Potential Therapeutic ApproachesPankita H. Pandya0Mary E. Murray1Karen E. Pollok2Jamie L. Renbarger3Indiana University School of Medicine, Riley CCRC 2641, 705 Riley Hospital Drive, Indianapolis, IN 46202, USAIndiana University School of Medicine, Riley CCRC 2623, 705 Riley Hospital Drive, Indianapolis, IN 46202, USAIndiana University School of Medicine, Research Building R4, 302D1044 West Walnut St., Indianapolis, IN 46202, USAIndiana University School of Medicine, Riley CCRC 2616, 705 Riley Hospital Drive, Indianapolis, IN 46202, USAInterplay among immune activation and cancer pathogenesis provides the framework for a novel subspecialty known as immunooncology. In the rapidly evolving field of immunooncology, understanding the tumor-specific immune response enhances understanding of cancer resistance. This review highlights the fundamentals of incorporating precision medicine to discover new immune biomarkers and predictive signatures. Using a personalized approach may have a significant, positive impact on the use of oncolytics to better guide safer and more effective therapies.http://dx.doi.org/10.1155/2016/4273943 |
| spellingShingle | Pankita H. Pandya Mary E. Murray Karen E. Pollok Jamie L. Renbarger The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches Journal of Immunology Research |
| title | The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches |
| title_full | The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches |
| title_fullStr | The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches |
| title_full_unstemmed | The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches |
| title_short | The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches |
| title_sort | immune system in cancer pathogenesis potential therapeutic approaches |
| url | http://dx.doi.org/10.1155/2016/4273943 |
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