Sulfur Dioxide and Emergency Department Visits for Stroke and Seizure

The purpose of this study was to assess an association between ambient sulfur dioxide and the number of emergency department (ED) visits for ischemic stroke and seizure. The study used data collected in a Vancouver (Canada) hospital in the years 1999–2003. Daily ED visits diagnosed as ministroke, st...

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Main Authors: Mieczysław Szyszkowicz, Eugeniusz Porada, Neil Tremblay, Eric Grafstein
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Stroke Research and Treatment
Online Access:http://dx.doi.org/10.1155/2012/824724
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author Mieczysław Szyszkowicz
Eugeniusz Porada
Neil Tremblay
Eric Grafstein
author_facet Mieczysław Szyszkowicz
Eugeniusz Porada
Neil Tremblay
Eric Grafstein
author_sort Mieczysław Szyszkowicz
collection DOAJ
description The purpose of this study was to assess an association between ambient sulfur dioxide and the number of emergency department (ED) visits for ischemic stroke and seizure. The study used data collected in a Vancouver (Canada) hospital in the years 1999–2003. Daily ED visits diagnosed as ministroke, stroke, or seizure were investigated using the case-crossover technique. Conditional logistic regression models were applied to estimate the odds ratios (ORs) and their respective 95% confidence intervals (CIs). The models included temperature and relative humidity in the form of natural splines. The results were reported for an increase in interquartile range ((IQR), IQR=1.9 ppb for SO2). Positive and statistically significant associations were obtained for SO2 and ischemic stroke for all patients (OR=1.12; CI 1.02, 1.23; lag 3) and for female patients (OR=1.17; CI 1.01, 1.33; lag 0). In the case of ED visits for seizure, for female patients the results were also statistically significant (OR=1.15; CI 1.02, 1.28; lag 1 and OR=1.18; CI 1.05, 1.32; lag 2). These findings suggest that cases of ischemic cerebrovascular accidents are associated with acute exposure to ambient sulfur dioxide.
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institution Kabale University
issn 2090-8105
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language English
publishDate 2012-01-01
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series Stroke Research and Treatment
spelling doaj-art-98828ec6b37f4a74919b62796ab5404f2025-02-03T01:26:23ZengWileyStroke Research and Treatment2090-81052042-00562012-01-01201210.1155/2012/824724824724Sulfur Dioxide and Emergency Department Visits for Stroke and SeizureMieczysław Szyszkowicz0Eugeniusz Porada1Neil Tremblay2Eric Grafstein3Population Studies Division, Health Canada, Ottawa, ON, K1A 0K9, CanadaPopulation Studies Division, Health Canada, Ottawa, ON, K1A 0K9, CanadaPopulation Studies Division, Health Canada, Ottawa, ON, K1A 0K9, CanadaDepartment of Emergency Medicine, Providence Health Care and St. Paul’s Hospital, Vancouver, BC, V6Z 1Y6, CanadaThe purpose of this study was to assess an association between ambient sulfur dioxide and the number of emergency department (ED) visits for ischemic stroke and seizure. The study used data collected in a Vancouver (Canada) hospital in the years 1999–2003. Daily ED visits diagnosed as ministroke, stroke, or seizure were investigated using the case-crossover technique. Conditional logistic regression models were applied to estimate the odds ratios (ORs) and their respective 95% confidence intervals (CIs). The models included temperature and relative humidity in the form of natural splines. The results were reported for an increase in interquartile range ((IQR), IQR=1.9 ppb for SO2). Positive and statistically significant associations were obtained for SO2 and ischemic stroke for all patients (OR=1.12; CI 1.02, 1.23; lag 3) and for female patients (OR=1.17; CI 1.01, 1.33; lag 0). In the case of ED visits for seizure, for female patients the results were also statistically significant (OR=1.15; CI 1.02, 1.28; lag 1 and OR=1.18; CI 1.05, 1.32; lag 2). These findings suggest that cases of ischemic cerebrovascular accidents are associated with acute exposure to ambient sulfur dioxide.http://dx.doi.org/10.1155/2012/824724
spellingShingle Mieczysław Szyszkowicz
Eugeniusz Porada
Neil Tremblay
Eric Grafstein
Sulfur Dioxide and Emergency Department Visits for Stroke and Seizure
Stroke Research and Treatment
title Sulfur Dioxide and Emergency Department Visits for Stroke and Seizure
title_full Sulfur Dioxide and Emergency Department Visits for Stroke and Seizure
title_fullStr Sulfur Dioxide and Emergency Department Visits for Stroke and Seizure
title_full_unstemmed Sulfur Dioxide and Emergency Department Visits for Stroke and Seizure
title_short Sulfur Dioxide and Emergency Department Visits for Stroke and Seizure
title_sort sulfur dioxide and emergency department visits for stroke and seizure
url http://dx.doi.org/10.1155/2012/824724
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AT eugeniuszporada sulfurdioxideandemergencydepartmentvisitsforstrokeandseizure
AT neiltremblay sulfurdioxideandemergencydepartmentvisitsforstrokeandseizure
AT ericgrafstein sulfurdioxideandemergencydepartmentvisitsforstrokeandseizure