Induction Versus Noninduction Antiviral Therapy for Chronic Hepatitis C Virus in Patients with Congenital Coagulation Disorders: A Canadian Multicentre Trial
BACKGROUND: Patients with congenital coagulation disorders and chronic hepatitis C virus (HCV) infection have multiple risk factors (ie, infection predominantly with genotype-1 HCV, long duration of the disease, HIV coinfection and male sex) for poor response to antiviral therapy. The present study...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2007-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2007/817198 |
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| _version_ | 1832545869983907840 |
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| author | A Chatterjee MG Swain SS Lee VG Bain K Peltekian K Croitoru PC Adams K Kaita J Teitel EJ Heathcote |
| author_facet | A Chatterjee MG Swain SS Lee VG Bain K Peltekian K Croitoru PC Adams K Kaita J Teitel EJ Heathcote |
| author_sort | A Chatterjee |
| collection | DOAJ |
| description | BACKGROUND: Patients with congenital coagulation disorders and chronic hepatitis C virus (HCV) infection have multiple risk factors (ie, infection predominantly with genotype-1 HCV, long duration of the disease, HIV coinfection and male sex) for poor response to antiviral therapy. The present study compared induction therapy with interferon-alpha (IFN-α)-2b with standard IFN-α2b therapy. Pegylated IFN was not available at the time that the study was initiated. |
| format | Article |
| id | doaj-art-98777e6ccc6242fba8df61633602d843 |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2007-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-98777e6ccc6242fba8df61633602d8432025-02-03T07:24:33ZengWileyCanadian Journal of Gastroenterology0835-79002007-01-01212919510.1155/2007/817198Induction Versus Noninduction Antiviral Therapy for Chronic Hepatitis C Virus in Patients with Congenital Coagulation Disorders: A Canadian Multicentre TrialA Chatterjee0MG Swain1SS Lee2VG Bain3K Peltekian4K Croitoru5PC Adams6K Kaita7J Teitel8EJ Heathcote9Department of Medicine, University of Toronto, Toronto, CanadaUniversity of Calgary, Calgary, CanadaUniversity of Calgary, Calgary, CanadaUniversity of Alberta, Edmonton, Alberta, CanadaDalhousie University, Halifax, Nova Scotia, CanadaMcMaster University, Hamilton, CanadaUniversity of Western Ontario, London, Ontario, CanadaUniversity of Manitoba, Winnipeg, Manitoba, CanadaDepartment of Medicine, University of Toronto, Toronto, CanadaDepartment of Medicine, University of Toronto, Toronto, CanadaBACKGROUND: Patients with congenital coagulation disorders and chronic hepatitis C virus (HCV) infection have multiple risk factors (ie, infection predominantly with genotype-1 HCV, long duration of the disease, HIV coinfection and male sex) for poor response to antiviral therapy. The present study compared induction therapy with interferon-alpha (IFN-α)-2b with standard IFN-α2b therapy. Pegylated IFN was not available at the time that the study was initiated.http://dx.doi.org/10.1155/2007/817198 |
| spellingShingle | A Chatterjee MG Swain SS Lee VG Bain K Peltekian K Croitoru PC Adams K Kaita J Teitel EJ Heathcote Induction Versus Noninduction Antiviral Therapy for Chronic Hepatitis C Virus in Patients with Congenital Coagulation Disorders: A Canadian Multicentre Trial Canadian Journal of Gastroenterology |
| title | Induction Versus Noninduction Antiviral Therapy for Chronic Hepatitis C Virus in Patients with Congenital Coagulation Disorders: A Canadian Multicentre Trial |
| title_full | Induction Versus Noninduction Antiviral Therapy for Chronic Hepatitis C Virus in Patients with Congenital Coagulation Disorders: A Canadian Multicentre Trial |
| title_fullStr | Induction Versus Noninduction Antiviral Therapy for Chronic Hepatitis C Virus in Patients with Congenital Coagulation Disorders: A Canadian Multicentre Trial |
| title_full_unstemmed | Induction Versus Noninduction Antiviral Therapy for Chronic Hepatitis C Virus in Patients with Congenital Coagulation Disorders: A Canadian Multicentre Trial |
| title_short | Induction Versus Noninduction Antiviral Therapy for Chronic Hepatitis C Virus in Patients with Congenital Coagulation Disorders: A Canadian Multicentre Trial |
| title_sort | induction versus noninduction antiviral therapy for chronic hepatitis c virus in patients with congenital coagulation disorders a canadian multicentre trial |
| url | http://dx.doi.org/10.1155/2007/817198 |
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