Splenic index score as a predictor of outcomes in metastatic non small cell lung cancer patients treated with immune checkpoint inhibitors

Splenic index score as a predictor of outcomes in metastatic non small cell lung cancer patients treated with immune checkpoint inhibitors

Abstract Introduction Immune checkpoint inhibitors (ICIs) targeting PD-1 and PD-L1 have emerged as promising treatments for advanced NSCLC patients without actionable mutations. However, predicting treatment response remains challenging, especially in second-line settings. Although PD-L1 is the only...

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Bibliographic Details
Main Authors: Volkan Aslan, Atiye Cenay Karabörk Kılıç, Nigar Rustamova Cennet, Talha alperen Yücel, Bediz kurt inci, Fatih gürler, Ahmet Özet, Nuriye Özdemir, Huseyin Koray Kilic, Ozan Yazıcı
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Immune checkpoint inhibitor
Splenic volume
mNSCLC
Systemic inflammation
NLR
Online Access:https://doi.org/10.1038/s41598-025-00708-w
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