Multinucleate cell angiohistiocytoma: a case series and literature review
Multinucleate cell angiohistiocytoma (MCAH) is a rare benign cutaneous entity. It classically presents as slowly progressive erythematous to violaceous papules on the distal extremities of middle-aged or elderly women. The entity may clinically resemble granuloma annulare, lichen planus, and several...
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Language: | English |
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Termedia Publishing House
2024-12-01
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Series: | Polish Journal of Pathology |
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Online Access: | https://www.termedia.pl/Multinucleate-cell-angiohistiocytoma-a-case-series-and-literature-review,55,55291,1,1.html |
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author | Carolyn Szwed Malgorzata Maj Lidia Rudnicka Joanna Czuwara |
author_facet | Carolyn Szwed Malgorzata Maj Lidia Rudnicka Joanna Czuwara |
author_sort | Carolyn Szwed |
collection | DOAJ |
description | Multinucleate cell angiohistiocytoma (MCAH) is a rare benign cutaneous entity. It classically presents as slowly progressive erythematous to violaceous papules on the distal extremities of middle-aged or elderly women. The entity may clinically resemble granuloma annulare, lichen planus, and several cutaneous vascular proliferations. Histologically, MCAH is characterized by vascular proliferation within the upper and mid-dermis, a mild perivascular inflammatory infiltrate, and characteristic bizarre-shaped multinucleate cells. To date, less than 200 cases have been reported in the literature. We present five of the best examples diagnosed in our department to further elucidate this peculiar entity for pathological recognition. |
format | Article |
id | doaj-art-985e9e364d8944529b7df8afaaf05d99 |
institution | Kabale University |
issn | 1233-9687 2084-9869 |
language | English |
publishDate | 2024-12-01 |
publisher | Termedia Publishing House |
record_format | Article |
series | Polish Journal of Pathology |
spelling | doaj-art-985e9e364d8944529b7df8afaaf05d992025-01-27T11:36:31ZengTermedia Publishing HousePolish Journal of Pathology1233-96872084-98692024-12-0175426126710.5114/pjp.2024.14570355291Multinucleate cell angiohistiocytoma: a case series and literature reviewCarolyn SzwedMalgorzata MajLidia RudnickaJoanna CzuwaraMultinucleate cell angiohistiocytoma (MCAH) is a rare benign cutaneous entity. It classically presents as slowly progressive erythematous to violaceous papules on the distal extremities of middle-aged or elderly women. The entity may clinically resemble granuloma annulare, lichen planus, and several cutaneous vascular proliferations. Histologically, MCAH is characterized by vascular proliferation within the upper and mid-dermis, a mild perivascular inflammatory infiltrate, and characteristic bizarre-shaped multinucleate cells. To date, less than 200 cases have been reported in the literature. We present five of the best examples diagnosed in our department to further elucidate this peculiar entity for pathological recognition.https://www.termedia.pl/Multinucleate-cell-angiohistiocytoma-a-case-series-and-literature-review,55,55291,1,1.htmlmultinucleate cell angiohistiocytoma multinucleate cells |
spellingShingle | Carolyn Szwed Malgorzata Maj Lidia Rudnicka Joanna Czuwara Multinucleate cell angiohistiocytoma: a case series and literature review Polish Journal of Pathology multinucleate cell angiohistiocytoma multinucleate cells |
title | Multinucleate cell angiohistiocytoma: a case series and literature review |
title_full | Multinucleate cell angiohistiocytoma: a case series and literature review |
title_fullStr | Multinucleate cell angiohistiocytoma: a case series and literature review |
title_full_unstemmed | Multinucleate cell angiohistiocytoma: a case series and literature review |
title_short | Multinucleate cell angiohistiocytoma: a case series and literature review |
title_sort | multinucleate cell angiohistiocytoma a case series and literature review |
topic | multinucleate cell angiohistiocytoma multinucleate cells |
url | https://www.termedia.pl/Multinucleate-cell-angiohistiocytoma-a-case-series-and-literature-review,55,55291,1,1.html |
work_keys_str_mv | AT carolynszwed multinucleatecellangiohistiocytomaacaseseriesandliteraturereview AT malgorzatamaj multinucleatecellangiohistiocytomaacaseseriesandliteraturereview AT lidiarudnicka multinucleatecellangiohistiocytomaacaseseriesandliteraturereview AT joannaczuwara multinucleatecellangiohistiocytomaacaseseriesandliteraturereview |