Comparison of mNGS with conventional methods for diagnosis of cryptococcal meningitis: a retrospective study

Comparison of mNGS with conventional methods for diagnosis of cryptococcal meningitis: a retrospective study

Abstract The application of metagenomic next-generation sequencing (mNGS) in the diagnosis of cryptococcal meningitis is relatively under characterized. Here, we retrospectively evaluated data from cryptococcal meningitis patients who were tested using mNGS and/or routine testing, including fungal c...

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Bibliographic Details
Main Authors: Zai-Jie Jiang, Jian-Chen Hong, Bi-Wei Lin, Wei-Qing Zhang, Qi-Chao Fan, Bi-Hui Yang, Xiang-Ping Yao
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
Metagenomic next-generation sequence
Conventional method
Cryptococcal meningitis
Diagnosis
Cerebrospinal fluid
Online Access:https://doi.org/10.1038/s41598-025-86481-2
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