The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy

BACKGROUND: The underlying mechanisms of hepatitis C virus (HCV) resistance to treatment are unknown. Signal transducers and activators of transcription (STAT) proteins play a critical role in antiviral defense.

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Main Authors: Sherif El-Saadany, Dina H Ziada, Hanan El Bassat, Wael Farrag, Hesham El-Serogy, Manal Eid, Manal Abdallah, Medhat Ghazy, Hoda A Salem
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2013/562765
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author Sherif El-Saadany
Dina H Ziada
Hanan El Bassat
Wael Farrag
Hesham El-Serogy
Manal Eid
Manal Abdallah
Medhat Ghazy
Hoda A Salem
author_facet Sherif El-Saadany
Dina H Ziada
Hanan El Bassat
Wael Farrag
Hesham El-Serogy
Manal Eid
Manal Abdallah
Medhat Ghazy
Hoda A Salem
author_sort Sherif El-Saadany
collection DOAJ
description BACKGROUND: The underlying mechanisms of hepatitis C virus (HCV) resistance to treatment are unknown. Signal transducers and activators of transcription (STAT) proteins play a critical role in antiviral defense.
format Article
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institution Kabale University
issn 0835-7900
language English
publishDate 2013-01-01
publisher Wiley
record_format Article
series Canadian Journal of Gastroenterology
spelling doaj-art-9848d8fd029d4f2a8869ece333c6c83d2025-02-03T01:20:05ZengWileyCanadian Journal of Gastroenterology0835-79002013-01-01272e13e1710.1155/2013/562765The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to TherapySherif El-Saadany0Dina H Ziada1Hanan El Bassat2Wael Farrag3Hesham El-Serogy4Manal Eid5Manal Abdallah6Medhat Ghazy7Hoda A Salem8Department of Tropical Medicine, Tanta University, Tanta, EgyptDepartment of Tropical Medicine, Tanta University, Tanta, EgyptDepartment of Tropical Medicine, Tanta University, Tanta, EgyptDepartments of Internal Medicine, Tanta University, Tanta, CanadaClinical Pathology, Faculty of Medicine, Tanta University, Tanta, CanadaClinical Pathology, Faculty of Medicine, Tanta University, Tanta, CanadaClinical Pathology, Faculty of Medicine, Tanta University, Tanta, CanadaDepartments of Internal Medicine, Tanta University, Tanta, CanadaClinical Pharmacy, Misr University for Science and Technology, 6th of October City, EgyptBACKGROUND: The underlying mechanisms of hepatitis C virus (HCV) resistance to treatment are unknown. Signal transducers and activators of transcription (STAT) proteins play a critical role in antiviral defense.http://dx.doi.org/10.1155/2013/562765
spellingShingle Sherif El-Saadany
Dina H Ziada
Hanan El Bassat
Wael Farrag
Hesham El-Serogy
Manal Eid
Manal Abdallah
Medhat Ghazy
Hoda A Salem
The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy
Canadian Journal of Gastroenterology
title The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy
title_full The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy
title_fullStr The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy
title_full_unstemmed The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy
title_short The Role of Hepatic Expression of STAT1, SOCS3 and PIAS1 in the Response of Chronic Hepatitis C Patients to Therapy
title_sort role of hepatic expression of stat1 socs3 and pias1 in the response of chronic hepatitis c patients to therapy
url http://dx.doi.org/10.1155/2013/562765
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