GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure

Autoantibodies to the γ-aminobutyric acid receptor, subtype B (GABAB), are a known cause of limbic encephalitis. The spectrum of clinical manifestations attributable to this antibody is not well defined at the present time. Here we present a case of GABAB encephalitis presenting with encephalopathy,...

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Main Authors: Matthew C. Loftspring, Eric Landsness, Lindsey Wooliscroft, Robert Rudock, Sally Jo, Kevin R. Patel
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Neurological Medicine
Online Access:http://dx.doi.org/10.1155/2015/812035
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author Matthew C. Loftspring
Eric Landsness
Lindsey Wooliscroft
Robert Rudock
Sally Jo
Kevin R. Patel
author_facet Matthew C. Loftspring
Eric Landsness
Lindsey Wooliscroft
Robert Rudock
Sally Jo
Kevin R. Patel
author_sort Matthew C. Loftspring
collection DOAJ
description Autoantibodies to the γ-aminobutyric acid receptor, subtype B (GABAB), are a known cause of limbic encephalitis. The spectrum of clinical manifestations attributable to this antibody is not well defined at the present time. Here we present a case of GABAB encephalitis presenting with encephalopathy, status epilepticus, dysautonomia, and acute heart failure. To our knowledge, heart failure and dysautonomia have not yet been reported with this syndrome.
format Article
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institution Kabale University
issn 2090-6668
2090-6676
language English
publishDate 2015-01-01
publisher Wiley
record_format Article
series Case Reports in Neurological Medicine
spelling doaj-art-9835245b8980440e8eb3fe9403669cd42025-02-03T01:30:51ZengWileyCase Reports in Neurological Medicine2090-66682090-66762015-01-01201510.1155/2015/812035812035GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart FailureMatthew C. Loftspring0Eric Landsness1Lindsey Wooliscroft2Robert Rudock3Sally Jo4Kevin R. Patel5Department of Neurology, Washington University, St. Louis, MO 63110, USADepartment of Neurology, Washington University, St. Louis, MO 63110, USADepartment of Neurology, Washington University, St. Louis, MO 63110, USADepartment of Neurology, Washington University, St. Louis, MO 63110, USADepartment of Neurology, Washington University, St. Louis, MO 63110, USADepartment of Neurology, Washington University, St. Louis, MO 63110, USAAutoantibodies to the γ-aminobutyric acid receptor, subtype B (GABAB), are a known cause of limbic encephalitis. The spectrum of clinical manifestations attributable to this antibody is not well defined at the present time. Here we present a case of GABAB encephalitis presenting with encephalopathy, status epilepticus, dysautonomia, and acute heart failure. To our knowledge, heart failure and dysautonomia have not yet been reported with this syndrome.http://dx.doi.org/10.1155/2015/812035
spellingShingle Matthew C. Loftspring
Eric Landsness
Lindsey Wooliscroft
Robert Rudock
Sally Jo
Kevin R. Patel
GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
Case Reports in Neurological Medicine
title GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_full GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_fullStr GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_full_unstemmed GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_short GABAB Encephalitis: A Fifty-Two-Year-Old Man with Seizures, Dysautonomia, and Acute Heart Failure
title_sort gabab encephalitis a fifty two year old man with seizures dysautonomia and acute heart failure
url http://dx.doi.org/10.1155/2015/812035
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