New application of ombuoside in protecting auditory cells from cisplatin-induced ototoxicity via the apoptosis pathway
Hearing loss is caused by many factors including ototoxic drug-induced hair cell damage. Ombuoside, an antioxidant isolated from Gynostemma pentaphyllum, has been suggested to serve as a new neuroprotective drug. However, the role of ombuoside in protecting inner ear hair cells from ototoxic drug-in...
Saved in:
| Main Authors: | Xingxing Wu, Xixia Peng, Yue Zhang, Wanjun Peng, Xiaochan Lu, Tingting Deng, Guohui Nie |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-10-01
|
| Series: | Heliyon |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405844024151973 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Sarsasapogenin protects hair cells from cisplatin-induced ototoxicity by attenuating apoptosis and ferroptosis via alleviating oxidative stress
by: Zhifeng Chen, et al.
Published: (2025-08-01) -
Strategies to Mitigate Cisplatin-Induced Ototoxicity: A Literature Review of Protective Agents, Mechanisms, and Clinical Gaps
by: Alexandru Orasan, et al.
Published: (2025-02-01) -
Ferulic Acid Combines with Ascorbic Acid to Target MMP9 to Attenuate Cisplatin-Induced Ototoxicity Through the p38MAPK Signaling Pathway
by: Guojun Yang, et al.
Published: (2025-05-01) -
Ototoxicity and long-term hearing outcome in pediatric patients receiving cisplatin
by: Tatpong Sriyapai, et al.
Published: (2022-06-01) -
Reversible p53 inhibition prevents cisplatin ototoxicity without blocking chemotherapeutic efficacy
by: Nesrine Benkafadar, et al.
Published: (2016-10-01)