The Effect of Age and Occupation on the Seroprevalence of Helicobacter pylori Infection
Serological studies in developed and developing countries using enzyme-linked immunosorbent assays have validated this technique as a rapid, noninvasive method for the diagnosis of Helicobacter pylori infections. The prevalence of serum antibodies to H pylori was studied in 473 Canadian blood donors...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
1992-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1992/831523 |
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| _version_ | 1832562547719405568 |
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| author | GI Perez-Perez T Marrie H Inouye T Shimoyama G Marshall G Meiklejohn MJ Blaser |
| author_facet | GI Perez-Perez T Marrie H Inouye T Shimoyama G Marshall G Meiklejohn MJ Blaser |
| author_sort | GI Perez-Perez |
| collection | DOAJ |
| description | Serological studies in developed and developing countries using enzyme-linked immunosorbent assays have validated this technique as a rapid, noninvasive method for the diagnosis of Helicobacter pylori infections. The prevalence of serum antibodies to H pylori was studied in 473 Canadian blood donors from Manitoba, 212 healthy Japanese. and 226 healthy Americans. As expected, the seroprevalence rose progressively with age in the three populations and reached its peak (greater than 55%) in subjects 60 years of age and older. The seroprevalence did not decrease in elderly persons (60 to 99 years), indicating a persistent immune response. More detailed analysis was perfom1ed on the Canadian population. Age-adjusted prevalence rates in men and women were similar.
Among young adults (15 to 29 years). farmers had a significantly higher seroprevalence rate than white-collar or blue-collar workers. but in older persons occupational rates were similar. A multiple linear
regression analysis of the data confirmed that age and occupation in young adults were both significantly associated with seroprevalence of H pylori infections. |
| format | Article |
| id | doaj-art-98067be6fef54b03a3f2f3efa9c23141 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 1992-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-98067be6fef54b03a3f2f3efa9c231412025-02-03T01:22:19ZengWileyCanadian Journal of Infectious Diseases1180-23321992-01-013313413810.1155/1992/831523The Effect of Age and Occupation on the Seroprevalence of Helicobacter pylori InfectionGI Perez-Perez0T Marrie1H Inouye2T Shimoyama3G Marshall4G Meiklejohn5MJ Blaser6Divisions of Infectious Diseases, Vanderbilt University School of Medicine and Veterans Administration Medical Center, Nashville, Tennessee, USADivision of Infectious Diseases, Dalhousie University, Halifax, Nova Scotia, CanadaHyogo College of Medicine, Nishinomiya, JapanHyogo College of Medicine, Nishinomiya, JapanDepartamento de Estadistica, Pontificia Universidad Católica de Chile, Santiago, ChileDivision of Infectious Diseases, University of Colorado School of Medicine, Denver, Colorado, USADivisions of Infectious Diseases, Vanderbilt University School of Medicine and Veterans Administration Medical Center, Nashville, Tennessee, USASerological studies in developed and developing countries using enzyme-linked immunosorbent assays have validated this technique as a rapid, noninvasive method for the diagnosis of Helicobacter pylori infections. The prevalence of serum antibodies to H pylori was studied in 473 Canadian blood donors from Manitoba, 212 healthy Japanese. and 226 healthy Americans. As expected, the seroprevalence rose progressively with age in the three populations and reached its peak (greater than 55%) in subjects 60 years of age and older. The seroprevalence did not decrease in elderly persons (60 to 99 years), indicating a persistent immune response. More detailed analysis was perfom1ed on the Canadian population. Age-adjusted prevalence rates in men and women were similar. Among young adults (15 to 29 years). farmers had a significantly higher seroprevalence rate than white-collar or blue-collar workers. but in older persons occupational rates were similar. A multiple linear regression analysis of the data confirmed that age and occupation in young adults were both significantly associated with seroprevalence of H pylori infections.http://dx.doi.org/10.1155/1992/831523 |
| spellingShingle | GI Perez-Perez T Marrie H Inouye T Shimoyama G Marshall G Meiklejohn MJ Blaser The Effect of Age and Occupation on the Seroprevalence of Helicobacter pylori Infection Canadian Journal of Infectious Diseases |
| title | The Effect of Age and Occupation on the Seroprevalence of Helicobacter pylori Infection |
| title_full | The Effect of Age and Occupation on the Seroprevalence of Helicobacter pylori Infection |
| title_fullStr | The Effect of Age and Occupation on the Seroprevalence of Helicobacter pylori Infection |
| title_full_unstemmed | The Effect of Age and Occupation on the Seroprevalence of Helicobacter pylori Infection |
| title_short | The Effect of Age and Occupation on the Seroprevalence of Helicobacter pylori Infection |
| title_sort | effect of age and occupation on the seroprevalence of helicobacter pylori infection |
| url | http://dx.doi.org/10.1155/1992/831523 |
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